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851-68-3

Basic Information
CAS No.: 851-68-3
Name: 2-methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine
Article Data: 4
Molecular Structure:
Molecular Structure of 851-68-3 (2-methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine)
Formula: C19H24 N2 O S
Molecular Weight: 328.478
Synonyms: Phenothiazine,10-[3-(dimethylamino)-2-methylpropyl]-2-methoxy- (6CI,8CI); (?à)-2-Methoxy-10-[3-(dimethylamino)-2-methylpropyl]phenothiazine;(?à)-Methotrimeprazine;10-[3-(Dimethylamino)-2-methylpropyl]-2-methoxyphenothiazine;dl-Methotrimeprazine
Density: 1.125g/cm3
Boiling Point: 468°Cat760mmHg
Flash Point: 236.8°C
Safety: Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of SOx and NOx.
PSA: 41.01000
LogP: 4.56060
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Toxicity Data With Reference

1.   

orl-rat LD50:1100 mg/kg

   27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,31.
2.   

scu-rat LD50:45 mg/kg

   27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,31.
3.   

orl-mus LD50:375 mg/kg

   PSCBAY    Psychopharmacology Service Center, Bulletin. 2 (1963),17.
4.   

ipr-mus LD50:110 mg/kg

   CRSBAW    Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 155 (1961),1029.
5.   

scu-mus LD50:300 mg/kg

   PSCBAY    Psychopharmacology Service Center, Bulletin. 2 (1963),17.
6.   

ivn-mus LD50:39 mg/kg

   PSDTAP    Proceedings of the European Society for the Study of Drug Toxicity. 9 (1968),159.
7.   

orl-bwd LD50:100 mg/kg

   TXAPA9    Toxicology and Applied Pharmacology. 21 (1972),315.

Safety Profile

Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of SOx and NOx.