Detail of "85603-33-4"
- CAS Number:
- 85603-33-4
- Name:
3-dimethylamino-1,1-diphenyl-1-prop-2-ynoxy-propan-2-one hydrochloride
- Molecular Structure:
- Formula:
- C20H22ClNO2
- Molecular Weight:
- 343.8472
- Density:
- g/cm3
- Boiling Point:
- 436.2°Cat760mmHg
- Flash Point:
- 217.6°C
3-dimethylamino-1,1-diphenyl-1-prop-2-ynoxy-propan-2-one hydrochloride
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Reference
- Ionization constants and partition coefficients of some 1,1-diphenyl-1-alkoxy-3-dialkylamino-2-propanones with analgesic activity
- Kourounakis, P.; Chilliard, N. (Dep. Pharm., Univ.In this study，85603-33-4 is also used. Thessaloniki, Thessaloniki, Greece). Pharmazie, 38(6), 388-9 (English) 1983. CODEN: PHARAT. ISSN: 0031-7144. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 22 The ionization consts. and the partition coeffs. (octanol/water) of a series of title compds. were detd. The influence of the alkyl group of the alkoxyl, the N substituents, and of the carbonyl group upon these physicochem. parameters is discussed. An attempt is made to correlate the analgesic activity of 1,1-diphenyl-1-phenoxy-3-dimethylamino-2-propanone [87199-09-5] and 1,1-diphenyl-1-ethoxy-3-piperidin-1-yl 2-propanone [87199-11-9] in terms of favorable pKa and partition coeff. values for these 2 derivs. .