Detail of "86-40-8"

Reference

Comparative investigations with Trypaflavin in metaphase-II oocytes and in dominant lethal assay

Comparative investigations with Trypaflavin in metaphase-II oocytes and in dominant lethal assay. Basler, A.; Brucklacher, M.; Nobis, F.; Roehrborn, G. (Inst. Humangenet. Anthropol., Univ. Duesseldorf, Duesseldorf, Ger.). Hum. Genet., 40(1), 87-92 (English) 1977. CODEN: HUGEDQ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Oral administration of 50 mg trypaflavin (I) [86-40-8]/kg to pregnant mice on day 7 of gestation induced dominant lethal mutation. When female mice were chronically treated with I (50 ′ 2 mg/kg/day, orally), the fertility of these animals decreased considerably, and various aberrations in oocytes were obsd.

Purification of homo- and hetero-oligonucleotides using high-performance charge-transfer chromatography

Purification of homo- and hetero-oligonucleotides using high-performance charge-transfer chromatography. Edwardson, Peter A. D.; Lowe, Christopher R.; Atkinson, Tony (Microbial Technol. Lab., PHLS Cent. Appl. Microbiol. Res.Several reagents with their cas registry numbers 86-40-8 and 92-62-6 are used here., Salisbury/Wiltshire SP4 0JG, UK). J. Chromatogr., 368(2), 363-9 (English) 1986. CODEN: JOCRAM. ISSN: 0021-9673. DOCUMENT TYPE: Journal CA Section: 9 (Biochemical Methods) Section cross-reference(s): 33 Oligonucleotides were purified by high-performance charge-transfer chromatog. using the dye acriflavin coupled to silica as the stationary phase. Numerous oligonucleotides were purified by using this technique. Homogeneity of oligonucleotides eluted from the acriflavin matrixes was detd. by electrophoresis on 20% polyacrylamide gels and in each case they were >90% pure. .