Products Categories
CAS No.: | 863-57-0 |
---|---|
Name: | GLYCOCHOLIC ACID SODIUM SALT |
Molecular Structure: | |
Formula: | C26H42NO6Na |
Molecular Weight: | 487.612 |
Synonyms: | Glycine,N-[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]-,monosodium salt (9CI);Glycine, N-choloyl-, monosodium salt (8CI);Cholane,glycine deriv.;Glycocholic acid sodium salt;Monosodium glycocholate;NSC35609;Sodium cholylglycinate; |
EINECS: | 212-730-9 |
Melting Point: | 210-215 °C |
Boiling Point: | 692oC at 760 mmHg |
Flash Point: | 372.3oC |
Appearance: | light green solid |
Safety: | 22-24/25 |
PSA: | 129.92000 |
LogP: | 1.62110 |
Conditions | Yield |
---|---|
With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; sodium hydroxide In water; dimethyl sulfoxide; acetonitrile; tert-butyl alcohol at 20 - 80℃; | 95% |
sodium glycocholate
[(R)-4-((5R,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Dihydroxy-10,13-dimethyl-3-oxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-acetic acid
Conditions | Yield |
---|---|
With DL-dithiothreitol; NAD In water; ethyl acetate for 40h; Ambient temperature; 3α-hydroxysteroid dehydrogenase, puryvate/lactic dehydrogenase, serum albumin, potassium phosphate buffer pH=8.5; Yield given; |
Conditions | Yield |
---|---|
With ethylenediaminetetraacetic acid; chloylglycine hydrolase; 2-hydroxyethanethiol In phosphate buffer at 20℃; for 0.333333h; pH=8; | A 100 % Chromat. B n/a |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 100 percent Chromat. / chloylglycine hydrolase; β-mercaptoethanol; EDTA / aq. phosphate buffer / 0.33 h / 20 °C / pH 8 2: 8 percent / Sepharose-CL6B; 7β-hydroxysteroid dehydrogenase; TEA / NAD(+) / H2O / 120 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 100 percent Chromat. / chloylglycine hydrolase; β-mercaptoethanol; EDTA / aq. phosphate buffer / 0.33 h / 20 °C / pH 8 2: 80 percent / Sepharose-CL6B; 7β-hydroxysteroid dehydrogenase; TEA / NAD(+) / H2O / 120 h / 20 °C View Scheme |
sodium glycocholate
glycocholic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NAD, DTT / ethyl acetate; H2O / 40 h / Ambient temperature; 3α-hydroxysteroid dehydrogenase, puryvate/lactic dehydrogenase, serum albumin, potassium phosphate buffer pH=8.5 2: NADH, DTT / ethanol; H2O / 30 h / 3β-hydroxysteroid dehydrogenase, formate/formate dehydrogenase, potassium phosphate buffer pH=7.2 View Scheme |
Conditions | Yield |
---|---|
In water at 25℃; pH=7; Thermodynamic data; Concentration; phosphate buffer; |
What can I do for you?
Get Best Price
The IUPAC name of Sodium glycocholate is sodium 2-[4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]acetate. With the CAS registry number 863-57-0, it is also named as Glycocholate sodium salt. The product's categories are Detergents; Bile Acids; Biochemistry; Steroids; Mutagenesis Research Chemicals. Besides, it is light green solid, which should be stored in sealed and dry place. This chemical is used in biological medium. In addition, its molecular formula is C26H42NO6Na and its molecular weight is 487.60. When you are using this chemical, please do not breathe dust. And you should avoid contact with skin and eyes.
The other characteristics of Sodium glycocholate can be summarized as: (1)EINECS: 212-730-9; (2)H-Bond Donor: 4; (3)H-Bond Acceptor: 6; (4)Rotatable Bond Count: 6; (5)Tautomer Count: 2; (6)Exact Mass: 487.290983; (7)MonoIsotopic Mass: 487.290983; (8)Topological Polar Surface Area: 130; (9)Heavy Atom Count: 34; (10)Complexity: 766; (11)Melting Point: 210-215 °C; (12)refractive index: 30 ° (C=1, H2O).
People can use the following data to convert to the molecule structure.
(1)SMILES: [Na+].[O-]C(=O)CNC(=O)CC[C@@H](C)[C@H]3CC[C@H]2[C@@H]4[C@H](O)CC1C[C@H](O)CC[C@]1(C)[C@H]4C[C@H](O)[C@@]23C
(2)InChI: InChI=1/C26H43NO6.Na/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);/q;+1/p-1/t14-,15,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1
(3)InChIKey: OABYVIYXWMZFFJ-KFPABCKBBN
(4)Std. InChI: InChI=1S/C26H43NO6.Na/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);/q;+1/p-1/t14-,15,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1
(5)Std. InChIKey: OABYVIYXWMZFFJ-IBWKMHYSA-M