Reference

Emulsions containing pantothenic acid derivatives

Emulsions containing pantothenic acid derivatives. (Shiseido Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 59173125 A2 1 Oct 1984 Showa, 6 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: B01F017-38; B01F017-44; B01J013-00. ICA: A23L001-24; A61K007-02; A61K009-10. APPLICATION: JP 83-46936 19 Mar 1983. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 18, 63 Emulsified compns. comprise (1) 1 or more of compds. selected from pantothenic acid [79-83-4], its salts, and pantothenyl Et ether [667-83-4], (2) sol. polyhydric alcs. contg. >2 OH groups in the mol., and (3) oils. These are stable emulsions useful in cosmetics and pharmaceuticals. Thus, an emulsion comprises Na pantothenate [867-81-2] 3, glycerin [56-81-5] 27, and jojoba oil 70% by wt.

Chromatographic study of vitamin B5 and its degradation products

Chromatographic study of vitamin B5 and its degradation products. Puech, A.; Monleaud, Mrs. J.; Jacob, M.; Lapiczak, G. (Lab. Pharm. Galenique, Fac. Pharm., Montpellier, Fr.). Ann. Pharm. Fr., 36(3-4), 191-5 (French) 1978. CODEN: APFRAD. ISSN: 0003-4509. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Section cross-reference(s): 63 Pantothenic acid (vitamin B5) [79-83-4], some of its salts, and some of its pharmaceutical degrdn. products were thin-layer-chromatographed at 18° on silica gel GF 254 with CHCl3-EtOH-HOAc (5:3.5:1.5). The plates were dried at 100° for 10 min, sprayed with 0.1N KMnO4 (pH 10.8), and dried at 100° for 10 min. The compds. appeared as yellow spots on a pink background; Rf values and sensitivities were, resp.: pantothenic acid, 0.80, 1.00 mg; Ca pantothenate [137-08-6], 0.76, 0.50 mg; Na pantothenate [867-81-2], 0.77, 0.50 mg; panthenol [81-13-0], 0.65, 0.50 mg; pantoyl lactone [599-04-2], 0.92, 0.05 mg; b-alanine [107-95-9], 0.08, 0.10 mg. These sensitivities were as good as or better than those obtainable with ninhydrin as spray reagent. When mixts. of the above compds. were sepd. by this method, the min. amts. detectable were increased slightly in some cases, and the Rf values fluctuated slightly. However, the Ca and Na salts remained the only substances which could not be resolved.