Detail of "87-00-3"

CAS Number:
87-00-3
Name:
Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
Superlist Name:
Homotropine
Molecular Structure:
Formula:
C16H21 N O3
Molecular Weight:
275.38
Synonyms:
1aH,5aH-Tropan-3a-ol, (?à)-mandelate (ester) (8CI);Benzeneacetic acid, a-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(?à)-; (?à)-Homatropine; (?à)-Mandelic acid 1aH,5aH-tropan-3a-ylester; (?à)-Mandelyltropine; Benzeneaceticacid, a-hydroxy-,8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-; Homatropin; Homatropine; Homoatropine;Mandelyltropeine; Tropine (?à)-mandelate (ester); Tropine mandelate
EINECS:
201-716-8
Density:
1.21 g/cm³
Melting Point:
100ºC
Boiling Point:
403.3 ºC
Flash Point:
197.7 ºC
Hazard Symbols:
Moderately toxic by ingestion and subcutaneous routes.
Safety:
A poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic vapors of NO_x. Details

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Supplier:Jinan Haohua Industry CO., LTD [ China (Mainland)]

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Determination of some pharmaceuticals using simple potentiometric sensors of coated-wire type: Determination of some pharmaceuticals using simple potentiometric sensors of coated-wire type. Vytras, Karel (Dep. Anal. Chem., Univ. Chem. Technol., Pardubice 532 10, Czech.). Mikrochim. Acta, 3(1-2), 139-48 (English) 1984. CODEN: MIACAQ. ISSN: 0026-3672. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) The title sensors were prepd. from an Al conductor and can monitor titrns. based on ion-pair formation. The central part of the conductor is coated with poly(vinyl chloride) [9002-86-2] and a plasticizer. Examples are given of cinchocaine [85-79-0], Septonex [10567-02-9], pilocarpine [92-13-7], ethylmorphine [76-58-4], and homatropine [87-00-3] detn. by the title sensors with sodium tetraphenylborate [143-66-8] as titrant.

Analysis of binary drug mixtures by ultraviolet spectrophotometry: Analysis of binary drug mixtures by ultraviolet spectrophotometry. Unfavorable cases. Parmentier, Alain; Barthelemy, Jean Francois; Andermann, Guy (Lab. POS, Cent. Rech., Kaysersberg 68240, Fr.). Labo-Pharma - Probl. Tech., 344, 536-9 (French) 1984. CODEN: LPPTAK. ISSN: 0458-5747. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) UV spectrophotometry permits the detn. of drug constituents of a mixt. of drugs in formulations. The drugs used in the mixt. are so chosen that they have very different absorbance max., one drug absorbing much weaker than the other in the UV spectral region. An equation is derived to calc. the absorbance and their ratios. The method was tested on 2 binary mixts. contg. (A) chlorhexidine [55-56-1] and thiomersal [54-64-8], and (B) homatropine [87-00-3] and Nipasept [8014-04-8]. The absorbances at 255 and 210 nm were chosen for the calcn. The method gives a precision of 4-6%, while the classical methods show an error of 20% with relative std. deviations 10-20%.