CAS No.88-16-4,2-Chlorobenzotrifluoride Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	88-16-4
Name:	2-Chlorobenzotrifluoride
Article Data:	36

Formula:	C₇H₄ClF₃
Molecular Weight:	180.557
Synonyms:	o-Chloro-.alpha.,.alpha.,.alpha.-trifluorotoluene;o-(Trifluoromethyl)phenyl chloride;2-Chloro-alpha,alpha,alpha-trifluorotoluene;Benzene, 1-chloro-2- (trifluoromethyl)-;o-(Trifluoromethyl)chlorobenzene;Chlorobenzotrifluoride;Benzene, 1-chloro-2-(trifluoromethyl)-;2-Chlorobenzotriflouride;O-chloro trifluorotoluene;2-chloro-α,α,α-trifluorotoluene;o-chlorobenzotrifluoride;2-chloro benzotri fluoride;o-Chloro-alpha,alpha,alpha-trifluorotoluene;1-Chloro-2-(trifluoromethyl)benzene;
EINECS:	201-805-1
Density:	1.338 g/cm³
Melting Point:	-7.4 °C
Boiling Point:	155.7 °C at 760 mmHg
Flash Point:	58.9 °C
Solubility:	<0.1 g/100 mL at 19.5 °C in water
Appearance:	clear colourless to light yellow liquid
Hazard Symbols:	Xn, F, Xi, N
Risk Codes:	10-36/37/38-22
Safety:	26-36-36/37/39-16
Transport Information:	UN 2234 3/PG 3
PSA:	0.00000
LogP:	3.35880

Synthetic route

: 615-41-8
2-iodochlorobenzene

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
In N,N,N,N,N,N-hexamethylphosphoric triamide; N,N-dimethyl-formamide at 60 - 70℃; for 6h;	84%

: 79-35-6
1,1'-dichloro-2,2'-difluoroethene

: 392-83-6
o-trifluoromethylphenyl bromide

A: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

B: 88444-77-3
1-(2,2-dichloro-1-fluoroethenyl)-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With n-butyllithium In diethyl ether for 1h; Heating;	A 3% B 77%

...Expand

: 160911-81-9
1-Chloro-2-(ethylsulfanyl-difluoro-methyl)-benzene

A: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

B: 115345-92-1
1-Chloro-2-(chloro-difluoro-methyl)-benzene

Conditions

Conditions	Yield
With bromine trifluoride In trichlorofluoromethane at 0℃;	A 70% B 5%
With bromine trifluoride; trichlorofluoromethane at 0℃;	A 70% B 5%

: 160911-76-2
2-Chloro-dithiobenzoic acid ethyl ester

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With bromine trifluoride In trichlorofluoromethane at 0℃; for 0.0333333h;	70%
Multi-step reaction with 2 steps 1: BrF3 / CCl3F / 0 °C 2: 70 percent / BrF3, CFCl3 / 0 °C View Scheme

: 615-41-8
2-iodochlorobenzene

: 2923-18-4
sodium 2,2,2-trifluoroacetate

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With potassium fluoride; potassium phosphate In water; N,N-dimethyl-formamide at 20℃; for 48h; Irradiation; Inert atmosphere;	63%
With 1-methyl-pyrrolidin-2-one; copper(l) iodide at 160℃; for 4h;	87 % Chromat.
With copper; silver(l) oxide In N,N-dimethyl-formamide at 130℃; for 15h; Inert atmosphere;	70 %Spectr.

: 694-80-4
2-bromo-1-chlorobenzene

: 2923-18-4
sodium 2,2,2-trifluoroacetate

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With potassium fluoride; potassium phosphate In water; N,N-dimethyl-formamide at 20℃; for 48h; Irradiation; Inert atmosphere;	39%

: 110-91-8
morpholine

: 320-60-5
2,4-dichloro-benzotrifluoride

A: 4-(3-chloro-4-trifluoromethylphenyl)morpholine

B: 98-56-6
4-chlorobenzotrifluoride

C: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With Adipic acid; N'-phenyloxalyl bishydrazide; copper diacetate; sodium acetate; cetyltrimethylammonim bromide; 2,5-hexanedione; potassium hydroxide In water at 110℃; for 3h; Inert atmosphere;	A 5% B n/a C n/a

...Expand

: 2136-89-2
2-chlorobenzotrichloride

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With hydrogen fluoride; antimonypentachloride
With antimony(III) fluoride
With hydrogen fluoride at 50℃; under 7500.75 Torr; for 1h; Autoclave;
With antimony (V)-fluoride chloride; phosphorus pentachloride; hydrogen fluoride
With hydrogen fluoride at 82℃; under 1500.15 - 13501.4 Torr; for 0.5h; Pressure; Temperature;

: 88-17-5
2-(trifluoromethyl)benzenamine

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuCl;

: 61841-46-1
2,3,5-trichlorotrifluoromethylbenzene

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

Conditions

Conditions	Yield
With Dichloromethylsilane at 240℃; (electron irradiation);

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Chemistry

IUPAC Name: 1-chloro-2-(trifluoromethyl)benzene
Synonyms: 2-Chloro-alpha,alpha,alpha-trifluorotoluene ; 1-Chloro-2-(trifluoromethyl)benzene; 2-Chloro(trifluoromethyl)benzene
Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Chlorine Compounds;Fluorine Compounds
Molecular Formula of 2-Chlorobenzotrifluoride (88-16-4): C₇H₄ClF₃
Molecular Weight: 180.55 g/mol
EINECS: 201-805-1
Melting point: -7.4 °C
Density: 1.338 g/cm³
Flash Point: 58.9 °C
Index of Refraction: 1.448
Surface Tension: 24.5 dyne/cm
Boiling Point: 155.7 °C at 760 mmHg
Enthalpy of Vaporization: 37.63 kJ/mol
Vapour Pressure: 3.85 mmHg at 25°C
storage temp.: Flammables area
Solubility: Insoluble in water, soluble in alcohol, ether, benzene .
Appearance of 2-Chlorobenzotrifluoride (88-16-4): clear colourless to light yellow liquid
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong bases
Following is the molecular structure of 2-Chlorobenzotrifluoride (88-16-4):

Uses

2-Chlorobenzotrifluoride (88-16-4) can be used for intermediates in synthetic pesticide, dyestuff and medicine that containing fluorine.

Toxicity Data With Reference

RTECS#: CAS# 88-16-4: XS9141000
LD50/LC50: RTECS:
CAS# 88-16-4: Oral, rat: LD50 = 1600 mg/kg;
Carcinogenicity: 2-Chlorobenzotrifluoride - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other: See actual entry in RTECS for complete information.

Safety Profile

Safty informations about 2-Chlorobenzotrifluoride (88-16-4):
Hazard Codes: Irritant Xi,F, Harmful Xn, Dangerous N
Risk Statements:10-36/37/38-22
R10: Flammable
R36/37/38:Irritating to eyes, respiratory system and skin
R22 :Harmful if swallowed
Safety Statements: 26-36-36/37/39-16
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36:Wear suitable protective clothing
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection
S16 :Keep away from sources of ignition - No smoking
RIDADR: UN 2234 3/PG 3
WGK Germany: 3
TSCA: T
HazardClass: 3
PackingGroup: III

Specification

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources.
Incompatibilities with Other Materials Strong oxidizing agents, strong reducing agents.
Hazardous Decomposition Products Hydrogen chloride, chlorine, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, fluorine, hydrogen fluoride gas.
Hazardous Polymerization Will not occur.