Reference

Regulation of lipid synthesis in soybeans by two benzoic acid herbicides

Regulation of lipid synthesis in soybeans by two benzoic acid herbicides. Muslih, Raad K.; Linscott, Dean L. (Dep. Agron., Cornell Univ., Ithaca, N. Y., USA). Plant Physiol., 60(5), 730-5 (English) 1977. CODEN: PLPHAY. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemicals) The effects of dinoben (I) [88-86-8] and 3-chloramben (II) [133-90-4] on lipid formation and on the incorporation of various substrates into lipids by intact seeds and subcellular fractions of germinating soybean (Glycine max) were studied. I (20 mg/mL) inhibited synthesis of total lipids 67%, neutral lipids 73%, glycolipids 51%, and phospholipids 39% in germinating seeds. When polar lipids were further analyzed, inhibition of individual lipid classes was also obsd. II (20 mg/mL) stimulated total lipid synthesis 25%. With the exception of the mitochondrial fraction where malonate thiokinase was absent, I inhibited up to 99% the incorporation of acetate and malonate into lipids, but did not inhibit acetyl-CoA and malonyl-CoA incorporation. II stimulated the incorporation of all substrates tested into lipids by all fractions except the mitochondrial fraction when malonate was the substrate. When I and II were used in combinations, II did not reverse the inhibitory effect of I. I inhibitory effect is specific and is assocd. with the acetate and malonate thiokinase systems. The II effect is stimulatory to either acetyl-CoA carboxylase or fatty acid synthetase or both.