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Detail of "88495-63-0"

  • CAS Number:
  • 88495-63-0
  • Name:

  • Artesunate

  • Molecular Structure:
  • Formula:
  • C19H28O8
  • Molecular Weight:
  • 384.42
  • Deleted CAS:
  • 83507-69-1, 91487-94-4, 112346-66-4, 252637-87-9, 1177476-35-5, 1236362-31-4
  • Synonyms:
  • Butanedioicacid,mono(decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl)ester, [3R-(3a,5ab,6b,8ab,9a,10b,12b,12aR*)]-;Butanedioic acid,mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]ester (9CI);Arinate;Armax 200;Arsumax;Artesunata;Artesunic acid;Asumax;Cosunate;Dihydroqinghasu hemsuccinate;Gsunate Forte;Plasmotrim;Plasmotrin;Qinghaozhi;Saphnate;WR 256283;Zysunate;
  • Density:
  • 1.31 g/cm3
  • Melting Point:
  • 132-135 °C
  • Boiling Point:
  • 502.1 °C at 760 mmHg
  • Flash Point:
  • 173.5 °C
  • Appearance:
  • white crystalline powder
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 20/21/22
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CAS No.88495-63-0 ArtesunateCompetitive Product

Assay:99%  Package:25kg/drum, ...Storage:store in a c...  Transportation:by air/sea  Application:Artesunate

1.Our production and packing are completed in GMP workshop and GLP test 2.minimum order:1 g 3.free sample available

Min. Order:1Kilogram

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CAS No.88495-63-0 ArtesunateCompetitive Product

Assay:99%  Appearance:White color ...  Package:1kg/Tin, 5kg...Storage:Store in dry...  Application:Pharm

Specification: USP/BP/EP/FCC Certification: GMP/DMF/HACCP/HALAL/KOSHER Expiry Time: 4 Years

Min. Order:1Kilogram

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CAS No.88495-63-0 ArtesunateCompetitive Product

Assay:99%  Appearance:White color ...  Package:1kg with Alu...  Application:for the trea...

Artesunate CAS#: 88495-63-0 Molecular formula: C19H28O8 Molecular weight: 384.42 Formulation: White color cream crystalline powder Purity: 99% Artesunate is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin.

Min. Order:1Kilogram

Supplier:Xi'an Rongsheng Biotechnology Co., Ltd. [ China (Mainland)]

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CAS No.88495-63-0 ArtesunateCompetitive Product

Assay:98.0-102% HP...  Appearance:A white crys...  Package:25KG/dumStorage:it should be...  Application:Anti-malaria...

Molecular Formula:C19H28O8 (384.34) Category:Anti-malarial drug

Min. Order:25Kilogram

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CAS No.88495-63-0 ArtesunateCompetitive Product

Assay:98%HPLC  Package:25kg/bag in ...Storage:Store in dry...  Application:Analytical S...

Artesunate

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CAS No.88495-63-0 Artesunate

Assay:≥98%  Appearance:powder or cr...  Package:10mg,20mg,1g...Storage:-20degree

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CAS No.88495-63-0 Artesunate

Assay:99%  Appearance:powder  Package:drum

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CAS No.88495-63-0 Artesunate

Assay:98%  Appearance:White to off...

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CAS No.88495-63-0 Artesunate

Assay:98%

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CAS No.88495-63-0 Artesunate

Artesunate---We supply this product in very competitive price.

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CAS No.88495-63-0 Artesunate

Artesunate

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Assay:99%

CP2010

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CAS No.88495-63-0 Artesunate

ARTESUNATE

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CAS No.88495-63-0 Artesunate

Artesunate is part of the artemisinin group of drugs that treat malaria and a semi-synthetic derivative of artemisinin.

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CAS No.88495-63-0 Artesunate

Artesunate is a well known anti malarial API. It is most widely used oral ACT. Our Artesunate is more than 99% pure. we have ready stock of Artesunate. For specification and other details feel free to conatct us

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CAS No.88495-63-0 Artesunate

Chemical Name: ARTESUNATE CAS No. 88495-63-0 Molecular Formula: C19H28O8 Formula Weight: 384.42

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Arteannuinum succinate CAS NO：88495-63-0 Specification:CP2005 Molecular Formula：C19H28O8 Molecular Weight：384.42

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Artesunate

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Artesunate

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CAS No.88495-63-0 Artesunate

C19H28 O8

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CAS No.88495-63-0 Artesunate

C19 H28 O8

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Reference

Action of sodium artesunate on [3H]uridine incorporation and cell membrane of mouse spleen cells
Action of sodium artesunate on [3H]uridine incorporation and cell membrane of mouse spleen cells. Song, Qianli; Lin, Xingyu; Zhang, Rende; Zhang, Huizhu (Lab. Immunobiochem., Shanghai Immunol. Inst., Shanghai 200025, Peop. Rep. China). Zhongguo Yaoli Xuebao, 8(1), 72-6 (Chinese) 1987. CODEN: CYLPDN. ISSN: 0253-9756. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Artesunic acid (I) [88495-63-0], an antimalarial from Artemisia annua, inhibited RNA synthesis in mouse spleen cells stimulated by Con A or in nonstimulated fibroblasts as evidenced by [3H]uridine incorporation. In mouse lymphocytes, I increased the membrane fluidity at <10 mg/mL, but decreased it at >10 mg/mL. In sheep red blood cells, I induced hemolysis at >10 mg/mL. The effect of I on nucleic acid formation and cell membrane may be nonspecific.
Analysis of artesunic acid and dihydroqinghaosu in blood by high-performance liquid chromatography with reductive electrochemical detection
Analysis of artesunic acid and dihydroqinghaosu in blood by high-performance liquid chromatography with reductive electrochemical detection. Zhou, Z. M.; Anders, J. C.; Chung, H.; Theoharides, A. D. (Inst. Chin. Mater. Med., Acad. Tradit. Chin. Med., Beijing 100700, Peop. Rep. China). J. Chromatogr., 414(1), 77-90 (English) 1987. CODEN: JOCRAM. ISSN: 0021-9673. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) A new HPLC method using reductive electrochem. detection has been developed for the anal. of the antimalarial drugs artesunic acid (ARTS) [88495-63-0] and dihydroquinghaosu (DQHS) (dihydroartemisinin) [71939-50-9] in blood. 71939-50-9 and 88495-63-0 are also in the experiment. Presently, this method has been validated to 4 mg/mL for ARTS and 200 ng/mL for DQHS. Pharmacokinetic studies in the rabbit show that after i.v. administration (100 mg/kg) ARTS is metabolized rapidly to DQHS and has a half-life (t1/2) of 1.7 min in blood. DQHS data were fit to nonlinear regression models consisting of the sum of 2 exponential terms. For phases 1 and 2, t1/2 values of 3.0 and 29 min were calcd., resp. In vitro studies in which ARTS was incubated with blood from various species show that rabbit blood hydrolyzes ARTS at a much greater rate than rat or human blood. Incubation of ARTS with rabbit blood in the presence or absence of diisopropylfluorophosphate suggested that this hydrolysis reaction is catalyzed by plasma and red blood cell esterases. These results suggest that future pharmacokinetic studies in both animals and man should focus on the measurement of DQHS rather than ARTS. .
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