Detail of "88732-96-1"

CAS Number:
88732-96-1
Name:
Aluminate(1-), (D-gluconato(2-)-O(sup 1),O(sup 2)dihydroxy-, (T-4)-, hydrogen, compd. with N-cyclohexyl-1-piperazineacetamide (1:1)

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Organometal complexes of N-cyclohexylpiperazinoacetamides or -propionamides and their use as ulcer- and secretion-preventative and buffering agents: Organometal complexes of N-cyclohexylpiperazinoacetamides or -propionamides and their use as ulcer- and secretion-preventative and buffering agents.There are some reagents like 88732-96-1 is used in this study. Corvi, Mora Camillo (Camillo Corvi S.p.A., Italy). Ger. Offen. DE 3310584 A1 13 Oct 1983, 10 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C07D295-14; A61K031-495; A61K031-19; A61K031-70. APPLICATION: DE 83-3310584 23 Mar 1983. PRIORITY: IT 82-20583 5 Apr 1982. 526-95-4 and 88732-95-0 are also in the experiment. DOCUMENT TYPE: Patent CA Section: 33 (Carbohydrates) Section cross-reference(s): 1, 28 Complex salts of N-cyclohexylpiperazinoacetamide or -propionamide with dihydroxyaluminum a-hydroxycarboxylates, useful as antiulcer, antisecretory, and buffering agents were prepd. Treating aq. gluconic acid with Al(OCHMe2)3 and stirring 4 h at 75° gave almost quant. Al gluconate which was treated with 10% of N-cyclohexyl-1-piperazineacetamide to give 97-98% yield of 98.5-99% pure piperazine aluminum gluconate I. The buffering activity of I was 156 mg/kg orally (rat), the antisecretory activity 330 mg/kg orally (rat), and the antiulcer activity 150-480 mg/kg (rat) for 7 types of ulcers. ..