CAS No.89396-94-1,(S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID Suppliers

Products Categories

Pharmaceutical (50)
Organic Chemicals (16)
Others (10)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	89396-94-1
Name:	(S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID
Article Data:	2

Formula:	C₂₀H₂₇N₃O₆^.HCl
Molecular Weight:	441.912
Synonyms:	4-Imidazolidinecarboxylic acid,3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-,monohydrochloride, [4S-[3[R(R)],4R*]]-;Novaloc;TA6366;Tanapril;Tanatril;
EINECS:	685-551-0
Melting Point:	38-42oC
Boiling Point:	577 °C at 760 mmHg
Flash Point:	302.8 °C
PSA:	116.25000
LogP:	1.14290

Raw Materials

943-73-7

Total:68 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 89396-94-1

Specification

The 4-Imidazolidinecarboxylicacid,3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-,hydrochloride (1:1), (4S)- , with the CAS register number 89396-94-1, has the systematic name of 4-Imidazolidinecarboxylic acid, 3-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1-methyl-2-oxo-, monohydrochloride, (4S-(3(R*(R*)),4R*))- . And it is also known to us as (s)-3-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-1-methyl-2-oxo-imidazolidine-4-carboxylic acid ; imidaprilhydrochloride ; 4-imidazolidinecarboxylic acid, 3-[(2s)-2-[[(1s)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, monohydrochloride, (4s)-;novaloc;ta 6366 ; tanapril ; (s)-3-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-1-methyl-2-oxo-imidazolidine-4-carboxylic acid: hydrochloride .

The characteristics of this chemical are as below:(1)ACD/BCF (pH 5.5): 1 ; (2)ACD/BCF (pH 7.4): 1 ; (3)ACD/KOC (pH 5.5): 1 ; (4) ACD/KOC (pH 7.4): 1 ; (5)#H bond acceptors: 9 ; (6)#H bond donors: 2 ; (7)#Freely Rotating Bonds: 10 ; (8)Polar Surface Area: 96.46 ; (9)Flash Point: 302.8 °C ; (10)Enthalpy of Vaporization: 90.88 kJ/mol ; (11)Boiling Point: 577 °C at 760 mmHg ; (12)Vapour Pressure: 3.71E-14 mmHg at 25°C.

This kind of chemical could be used in many fields, such as angiotensin-converting enzyme inhibitors, antihypertensive agents, cardiovascular agents, drug / therapeutic agent, enzyme inhibitors and protease inhibitors.

You could also convert the following data information into the molecular structure:
SMILES:O=C(O)[C@H]2N(C(=O)[C@@H](N[C@H](C(=O)OCC)CCc1ccccc1)C)C(=O)N(C)C2.Cl
InChI:InChI=1/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
InChIKey:LSLQGMMMRMDXHN-GEUPQXMHBC

As to the market information, there are many supplier in China, such as LGM Pharmaceuticals Inc. Hangzhou Sunny Chemical Co., Ltd. and Link Chemicals Co.,Ltd.

In addition, you could get the toxicity information:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
dog	LD50	oral	> 1800mg/kg (1800mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.
mouse	LD50	intravenous	> 500mg/kg (500mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.
mouse	LD50	oral	> 5gm/kg (5000mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.
mouse	LD50	subcutaneous	> 1gm/kg (1000mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.
rat	LD50	intravenous	> 500mg/kg (500mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.
rat	LD50	oral	3536mg/kg (3536mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.
rat	LD50	subcutaneous	> 1gm/kg (1000mg/kg)	Drugs in Japan Vol. -, Pg. 165, 1995.