Products Categories
Basic Information
| CAS No.: | 894-71-3 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Name: | NORTRIPTYLINE HYDROCHLORIDE | ||||||||||||
| Molecular Structure: | |||||||||||||
|
|
|||||||||||||
| Formula: | C19H21 N . Cl H | ||||||||||||
| Molecular Weight: | 299.843 | ||||||||||||
| Synonyms: | 1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride(9CI); 5H-Dibenzo[a,d]cycloheptene-D5,g-propylamine,10,11-dihydro-N-methyl-, hydrochloride (8CI);10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-D5,g-propylamine hydrochloride; 38489; 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptenehydrochloride; 5-[3-(Methylamino)propylidene]dibenzo[a,e]cyclohepta[1,5]dienehydrochloride; Acetexa; Allegron; Altilev; Aventyl hydrochloride;Desmethylamitriptyline hydrochloride; Noramitriptyline hydrochloride; Noritren;Nortrilen; Nortriptyline hydrochloride; Norzepine; Pamelor; Psychostyl;Sensival; Vividyl | ||||||||||||
| Melting Point: | 217-220?C | ||||||||||||
| Boiling Point: | 403.4°C at 760 mmHg | ||||||||||||
| Flash Point: | 194.9°C | ||||||||||||
| Hazard Symbols: | Xn,T,F | ||||||||||||
| Risk Codes: | 22-36/38-23/25-11 | ||||||||||||
| Safety: |
|
||||||||||||
| PSA: | 12.03000 | ||||||||||||
| LogP: | 5.01930 | ||||||||||||
Related products
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
- 926293-55-26-Bromo-2-methylpyridine-3-carboxaldehyde
- 911112-05-55-Iodo-3-(trifluoromethyl)-2-pyridinamine
- 95789-13-21,3,7-trimethylpurine-2,6-dione
- 956104-42-02-Bromo-5-nitro-3-(trifluoromethyl)pyridine
Synthetic route
Conditions
| Conditions | Yield |
|---|---|
| With sodium In methanol at 55℃; for 12h; Inert atmosphere; | 99% |
- 894-71-3
nortriptyline hydrochloride
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: nortriptyline hydrochloride; tetramethylammonium trifluoromethanethiolate With triethylamine In acetonitrile at 20℃; Stage #2: With silver fluoride In acetonitrile at 50℃; for 4h; | 98% |
Conditions
| Conditions | Yield |
|---|---|
| With dmap; diethylamino-sulfur trifluoride In acetonitrile at 25℃; under 760.051 Torr; for 2h; Schlenk technique; | 92% |
- 57294-38-9
N-(tert-butoxycarbonyl)-4-aminobutanoic acid
- 894-71-3
nortriptyline hydrochloride
- 1002331-77-2
tert-butyl 3-((10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-yllidene)-N-methylcarbamoyl)propylcarbamate
Conditions
| Conditions | Yield |
|---|---|
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; Industry scale; | 88% |
Conditions
| Conditions | Yield |
|---|---|
| With potassium carbonate In acetonitrile at 100℃; for 12h; Inert atmosphere; | 77% |
Conditions
| Conditions | Yield |
|---|---|
| In dichloromethane for 24h; Ambient temperature; | 63% |
- 894-71-3
nortriptyline hydrochloride
- 74427-22-8
2,2-difluoroethyl triflate
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: nortriptyline hydrochloride With N-ethyl-N,N-diisopropylamine In tetrahydrofuran Reflux; Stage #2: 2,2-difluoroethyl triflate In tetrahydrofuran at 5 - 20℃; for 14h; Stage #3: With hydrogenchloride In diethyl ether at 5℃; | 53% |
Conditions
| Conditions | Yield |
|---|---|
| With dmap; diethylamino-sulfur trifluoride In acetonitrile at 25℃; under 760.051 Torr; for 2h; Schlenk technique; | 50% |
- 1224597-89-0
pyridin-4-yl N,N,N’,N’-tetramethyldiamidophosphate
- 894-71-3
nortriptyline hydrochloride
Conditions
| Conditions | Yield |
|---|---|
| With TurboGrignard In tetrahydrofuran at 0 - 25℃; for 8h; Inert atmosphere; | 43% |
Conditions
| Conditions | Yield |
|---|---|
| With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; | 33% |
| With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; | 33% |
