Reference

Experimental animal studies on the effects of plant hydrocolloids (swelling substances) on intestinal absorption

Experimental animal studies on the effects of plant hydrocolloids (swelling substances) on intestinal absorption. Foerster, H.; Hoos, I. (Zent. Biol. Chem., Univ. Frankfurt/Main, Frankfurt/Main, Ger.). Z. Ernaehrungswiss., 16(2), 140-9 (German) 1977. CODEN: ZERNAL. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Injection of Na alginate [9005-38-3], K alginate [9005-36-1], calcium alginate [9005-35-0], carrageenan [9000-07-1], guaran [9000-30-0], methylcellulose [9004-67-5], or CM cellulose [9000-11-7], into rat intestine did not affect glucose [50-99-7] or maltose [69-79-4] absorption. The hydrolysis of maltose was not affected by the hydrocolloids. Na was absorbed from the intestinal lumen if the concn. was >120-150 mmoles/L; otherwise it was excreted into the lumen. K absorption was increased if the K concn. was raised above 6-10 mmoles/L; otherwise it was excreted into the lumen. Neutral gums did not alter ion concn. in the lumen.

Alginates; affirmation of GRAS status with certain limitations

Alginates; affirmation of GRAS status with certain limitations. Anon. (Food Drug Adm., Washington, D. C., USA). Fed. Regist., 43(19), 3725-8, (English) 27 Jan 1978. CODEN: FEREAC. ISSN: 0097-6326. DOCUMENT TYPE: Journal CA Section: 17 (Foods) Section cross-reference(s): 4 A summary of a literature survey from 1920 is given which considers chem. toxicity, occupational hazards, metab. reaction products, degrdn. products, toxicol. effects, detection and processing of alginates. It is concluded that there is no evidence on NH4 [9005-34-9], Ca [9005-35-0], K [9005-36-1], Na [9005-38-3], and propylene glycol alginates [9005-37-2] that suggests a hazard to the public when these compds. are used at levels that are now current. It is therefore proposed to affirm the generally recognized as safe (GRAS) status of these compds. as direct human food ingredients with specific limitations.