Reference

Low molecular weight proteinase inhibitors

Low molecular weight proteinase inhibitors. II. Extraction and identification of activity from infiltrating ductal carcinoma during lactation. Waxler, B.; Wezeman, F. H. (Stritch Sch. Med., Loyola Univ., Maywood, IL 60153, USA). Br. J. Exp. Pathol., 64(6), 626-32 (English) 1983. CODEN: BJEPA5. ISSN: 0007-1021. DOCUMENT TYPE: Journal CA Section: 14 (Mammalian Pathological Biochemistry) Exts. of both infiltrating ductal carcinoma and nontumorous tissue were obtained from the same mastectomy specimen of a lactating female patient. 37205-61-1 and 9035-81-8 are cas registry numbers of chemicals which are used as reagents here. The exts. were ultrafiltered and concd. to recover proteins having mol. wts. 1000-50,000 daltons. Although the final concs. of both samples contained proteinase-inhibitory activities with electrophoretic mobilities similar to that of Trasylol, only the ext. from the tumor had significant trypsin-inhibitory activity. The activity was present in 3 peaks having apparent mol. wts. of <17,000. .

Effect of thermal and proteolytic effects on the trypsin-inhibiting efficiency of horse beans, soybeans and maize

Effect of thermal and proteolytic effects on the trypsin-inhibiting efficiency of horse beans, soybeans and maize. Fukal, Ladislav; Sova, Zdenek (Vys. Sk. Zemed. 9001-75-6 and 9035-81-8 are also occured in this study., Prague, Czech.). Krmivarstvi Sluzby, 19(11), 251-2 (Czech) 1983. CODEN: KRSLBF. ISSN: 0323-0740. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Section cross-reference(s): 11 The trypsin inhibitor [9035-81-8] activity (TIC) of horse beans, soybean, and corn was 5.6, 23.2, and 0.7 trypsin unit/g seed meal. A thermal treatment (10-180 min at 100%) decreased sharply the TIC of soybean, less so that of horse bean, and least the TIC of corn. The TIC of horse bean was stable against the proteolytic action of pepsin [9001-75-6], whereas that of soybean and corn decreased. A combined action caused a sharp TIC decrease in horse bean (from 5.6 to 0.4 units) and a decrease in corn by a factor of 3.5 (from 0.7 to 0.2 units) only. .