Reference

Cosmetics containing nucleic acids, polysaccharides, and plant extracts

Cosmetics containing nucleic acids, polysaccharides, and plant extracts. (Kobayashi Kose Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 59134706 A2 2 Aug 1984 Showa, 3 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K007-00. APPLICATION: JP 83-5944 19 Jan 1983. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Cosmetics, which improve skin metab. and maintain moisture, consist of (1) nucleic acids, (2) a moisture-holding component (amino acids, peptides, polysaccharides, etc.), and (3) physiol. active agents (vitamins, enzymes, plant exts. etc.). Thus, a cream comprises petrolatum 1, liq. paraffin 10, wheat germ oil 5, stearic acid 1.5, sorbitan sesquioleate 1.5, perfume 0.1, 1,3-butylene glycol 3, carboxyvinyl polymer 0.01, DNA Na salt 1, Na hyaluronate [9067-32-7] 0.2, Tohki ext. 1, preservative 0.1, NaOH 0.005, and H2O to 100% by wt.

Corneal endothelial loss with new intraocular lenses

Corneal endothelial loss with new intraocular lenses. Barrett, G.; Constable, I. J. (Lions Eye Inst., Queen Elizabeth II Med. Cent., Nedlands 6009, Australia). Am. J. Ophthalmol., 98(2), 157-65 (English) 1984. CODEN: AJOPAA. ISSN: 0002-9394. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) When the effect of a hydrogel intraocular lens on the corneal endothelium of rabbits was compared to the damage produced by uncoated poly(Me methacrylate) [9011-14-7] (PMMA) intraocular lenses and PMMA lenses coated with Na hyaluronate [9067-32-7] or Me cellulose [9004-67-5], the endothelial damage produced by the hydrogel lenses in a std. 0.25 mm2 of contact was 3.6%. This value was not significantly different from that for the control corneas (0.4%). Uncoated PMMA lenses caused 62% endothelial loss but coating them with Na hyaluronate or Me cellulose reduced the loss to 27% and 57% resp. Thus, a hydrogel intraocular lens produces minimal endothelial damage and coating a PMMA lens with Na hyaluronate or Me cellulose does not provide reliable endothelial protection.