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Detail of "93793-83-0"

  • CAS Number:
  • 93793-83-0
  • Name:

  • Roxatidine acetate hydrochloride

  • Molecular Structure:
  • Formula:
  • C19H28N2O4.ClH
  • Molecular Weight:
  • 384.95
  • Deleted CAS:
  • 97744-01-9
  • Synonyms:
  • Altat (TN);Roxatidine acetate hydrochloride (JAN/USAN);Acetamide,2-(acetyloxy)-N-[3-[3-(1- piperidinylmethyl)phenoxy]propyl]-,monohydrochloride;Altat;Roxatidine aceacetate HCl;Acetamide,2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-monohydrochloride;Roxatidine Acetate HCl;
  • Boiling Point:
  • 537.3 °C at 760 mmHg
  • Flash Point:
  • 278.7 °C
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CAS No.93793-83-0 Roxatidine acetate hydrochlorideCompetitive Product

Other names:Gastralgin, Roxit, Altat, Xarcin Systematic name:N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]acetoxyacetamide hydrochloride

Supplier:SOGA ENTERPRISES ASIA GROUP [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Assay:99%  Appearance:White OR off...  Package:25kg/drumStorage:Normal tempe...  Transportation:general

Supplier:Jinan Jianfeng Chemical Co., Ltd [ China (Mainland)]

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Address:NO.9 HUANENG ROAD JINAN CITY, CHINA

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Category : Intermediates/Pharmaceutical intermediates CAS NO : 93793-83-0 EC NO : MF : C19H29ClN2O4 MW : 384.8976 Synonyms : Roxatidine Acetate HCL;2-oxo-2-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)ethyl acetate hydrochloride (1:1);

Supplier:Tianjin Yaoyu Chemicals co.,ltd [ China (Mainland)]

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Address:No.101, 1F, Beian Huating Community, ShengLi Road, Hebei District, Tianjin, China

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

CAS 93793-83-0

Supplier:Jinan Wedo Industrial Co., Ltd. [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

roxatidine acetate hydrochloride

Supplier:TCS INDUSTRY LIMITED [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Assay:98%

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Assay:JP/99%+

Supplier:Changzhou Highassay Chemical Co., Ltd [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:LIDE PHARMACEUTICALS LIMITED [ China (Mainland)]

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Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:Suzhou Howsine Biological Technology Co.,Ltd [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:Afine Chemicals Limited [ China (Mainland)]

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Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Roxatidine Acetate HCl

Supplier:hangzhou forewin pharma co.,Ltd. [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Product name: Roxatidine acetate hydrochloride Other name: 2-acetoxy-n-(3-(3-(1-piperidinomethylphenoxy)propyl)acetamide hydrochloride CAS number:93793-83-0 Molecular structure: Molecular formula: C19H28N2O4.HCl Molecular weight:384.90

Supplier:XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD [ China (Mainland)]

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Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Other names:Gastralgin, Roxit, Altat, Xarcin Systematic name:N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]acetoxyacetamide hydrochloride

Supplier:Super Chemicals Factory [ China (Mainland)]

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Address:jiangsu province,china

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Roxatidine acetate hydrochloride

Supplier:Hangzhou Reono Supplement Co.ltd [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Roxatidine Acetate

Supplier:Jai Radhe Sales [ India]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Roxatidine Acetate HCl

Supplier:Manus Aktteva Biopharma LLP [ India]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

assays ﹥98.5%

Supplier:hangzhou hysen pharm co.ltd [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:Jiangsu Baosheng Longcheng Pharmaceutical Co., Ltd, [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:FOND EVER CO.,LIMITED [ China (Mainland)]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:ETA SCIENTIFIC Co.,Ltd [ United Kingdom]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:Atlanta Associates [ India]

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CAS No.93793-83-0 Roxatidine acetate hydrochloride

Supplier:EstechPharma Co., Ltd. [ Korea]

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Reference

Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460)
Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460). Herling, A. W.; Becht, M.; Kelker, W.; Ljungstroem, M.; Bickel, M. (Dep. Pharmacol., Hoechst A.-G., Frankfurt/Main D-6230, Fed. Rep. Ger.). Agents Actions, 20(1-2), 35-9 (English) 1987. CODEN: AGACBH. ISSN: 0065-4299. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Acid secretion in isolated rabbit gastric glands was measured by means of the 14C-aminopyrine accumulation technique. HOE 760 (TZU-0460) [93793-83-0] and HOE 062 [97900-88-4], the desacetylated compd. of HOE 760, caused a concn.-dependent redn. of histamine (100 mM) induced aminopyrine-accumulation. The 50% inhibitory concn. (IC50) values were 3.16 and 1.58 mM for Hoe 760 and Hoe 062, resp. In comparison, an IC50 of 9.0 mM was obtained for cimetidine and 3.3 mM for ranitidine. The IC50 values of ranitidine, Hoe 760, and Hoe 062 were different from that of cimetidine. The addn. of increasing concns. of Hoe 760 parallel shifted the histamine concn.-response curve to the right. The transformation of these concn.-response curves indicated that this inhibition was caused by a competitive antagonism of the histamine receptor on the parietal cell. In agreement with these findings, the dibutyryl-cAMP-stimulated aminopyrine accumulation remained unaffected by the H2-receptor antagonists.
Inhibition of acetylcholinesterase by histamine-H2-receptor antagonists
Inhibition of acetylcholinesterase by histamine-H2-receptor antagonists. Aono, Mitsuri; Morika, Motoyuki; Mizuda, Kazuhiko; Narusawa, Hiroaki; Uchino, Haruto (Med. Sch., Kyoto Univ., Kyoto, Japan). Nippon Shokakibyo Gakkai Zasshi, 81(7), 1653 (Japanese) 1984. CODEN: NIPAA4. ISSN: 0369-4259. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 7 Histaminergic H2-receptor antagonists dose-dependently inhibited the activity of acetylcholinesterase [9000-81-1] and pseudocholinesterase [9001-08-5] in human blood and rat tissues. Ranitidine [66357-35-5] had the highest inhibitory activity on acetylcholinesterase, followed by cimetidine [51481-61-9], TZU0460 [93793-83-0], and YM11170 [76824-35-6]. TZU0460 showed the highest inhibitory activity on pseudocholinesterase, followed by ranitidine, YM11170, and cimetidine. The ratio of acetylcholinesterase-to-pseudocholinesterase in gastric mucosa, stomach, and brain was 1.94, 1.03, and 3.98, resp.
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