Detail of "95-73-8"

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CAS Number:
95-73-8
Name:
2,4-Dichlorotoluene
Molecular Structure:
Formula:
C₇H₆Cl₂
Molecular Weight:
161.03
Synonyms:
Toluene,2,4-dichloro- (8CI);1,3-Dichloro-4-methylbenzene;2,4-Dichloro-1-methylbenzene;
EINECS:
202-445-8
Density:
1.242 g/cm³
Melting Point:
-14 °C
Boiling Point:
198.6 °C at 760 mmHg
Flash Point:
79.4 °C
Solubility:
immiscible with water
Appearance:
clear colorless liquid
Hazard Symbols:
Xi
Risk Codes:
36/37/38
Safety:
23-24/25 Details
Transport Information:
UN 2810

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Reference

Reactions on Ziegler-Natta catalysts: Reactions on Ziegler-Natta catalysts. 15. Introduction of halogenated aralkyl groups into 1,4-polybutadiene and metathesis degradation of the modified polymers. Demel, Hans; Hummel, Klaus (Inst. Org. Chem. Org.-Chem. Technol., Tech. Univ. Graz, Graz, Austria). Makromol. Chem., 178(6), 1699-706 (German) 1977. CODEN: MACEAK. DOCUMENT TYPE: Journal CA Section: 35 (Synthetic High Polymers) 1,4-Polybutadiene [9003-17-2] was aralkylated with p-MeC6H4F [352-32-9], o- [95-49-8], m- [108-41-8], and p-MeC6H4Cl [106-43-4], p-BrC6H4Me [106-38-7], 2-chloro-p-xylene [95-72-7], and 2,4- [95-73-8] and 3,4-dichlorotoluene [95-75-0] in the presence of dicumyl peroxide [80-43-3]. The IR spectra of the products were detd., and the polymers were metathesized by 4-octene [592-99-4] and the products identified by gas chromatog.-mass spectroscopy. Aralkylation was accompanied by methylation.

In vitro cytotoxicity of organic pollutants to bluegill sunfish (BF-2) cells: In vitro cytotoxicity of organic pollutants to bluegill sunfish (BF-2) cells. Babich, H.; Borenfreund, E. (Lab. Anim. Res. Cent., Rockefeller Univ. 106-48-9 and 108-39-4 are cas registry numbers. These chemicals are also mentioned in this article., New York, NY 10021, USA). Environ. Res., 42(1), 229-37 (English) 1987. CODEN: ENVRAL. ISSN: 0013-9351. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) BF-2 cells, an established cell line derived from bluegill sunfish (Lepomis macrochirus), were exposed to 18 org. toxicants, with cytotoxicity being assayed by the neutral red (NR) technique. Based on the concn. of toxicant that reduced lysosomal uptake of NR by 50% (NR50), the rank order of cytotoxicity was methylmercury > pentachlorophenol [87-86-5] 2,3,5,6-tetrachlorophenol [935-95-5] > 2,3,5-trichlorophenol [933-78-8] > 2,3-dinitrotoluene (I) [602-01-7] > 2,4,6-trichlorophenol [88-06-2] > 2,4-dichlorophenol [120-83-2] > 2,4-dichlorotoluene [95-73-8] > 6-chloro-3-hydroxytoluene [59-50-7] > o-chlorotoluene [95-49-8] > 4-chlorophenol [106-48-9] > 2-chlorophenol [95-57-8], 2,4-dimethylphenol [105-67-9] > 2,4-dinitrophenol [51-28-5] > 4-nitrophenol [100-02-7] > 3-methylphenol [108-39-4] > phenol [108-95-2] > toluene [108-88-3]. Published in vivo median lethal concn. (LC50) values were identified for 11 of the 18 test agents and, with the exception of 2,4-dinitrophenol, there was a good correlation between the in vitro cytotoxicity of the test agents and their in vivo waterborne acute toxicity. The potencies of the substituted phenolics and chlorianted toluenes as detd. by the in vitro cytotoxicity assay correlated strongly with their log octanol/water partition coeffs. (log P). However, the toxicity of 2,3-dinitrotoluene in vitro, and apparently also in vivo, was not a function of its log P value. .

Detail of "95-73-8"

2,4-Dichlorotoluene

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Reference