Detail of "95-86-3"

Reference

Chemical mutagenesis testing in Drosophila

Chemical mutagenesis testing in Drosophila. II. Results of 20 coded compounds tested for the National Toxicology Program. Zimmering, S.; Mason, J. M.; Valencia, R.; Woodruff, R. C. (Div. Biol. Med., Brown Univ., Providence, RI 02912, USA). Environ. Mutagen., 7(1), 87-100 (English) 1985. CODEN: ENMUDM. ISSN: 0192-2521. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Results are presented from mutagenesis testing in Drosophila of 20 coded compds. Two compds. were pos. in the sex-linked recessive lethal test, and 2 were inconclusive. The pos. compds. were CaCrO4 in adult feeding expts. and ferrocene [102-54-5] after adult injection. The 2 inconclusive compds. were 2,4-diaminophenol [95-86-3] and hexachlorocyclopentadiene [77-47-4]. Compds. that produced a pos. response were assayed for chromosome breakage using the conventional translocation test. CaCrO4 was neg. in the translocation test, and ferrocene was pos. Many of the test compds. were poorly sol. in water, raising questions regarding the effective concn. to which the flies were exposed.

Study of the electrochemical reduction of nitroaniline isomers by the rotating ring-disk electrode method

Study of the electrochemical reduction of nitroaniline isomers by the rotating ring-disk electrode method. II. Acid solutions. Nekrasov, L. N.; Berdnikova, I. P. (USSR). Elektrokhimiya, 14(6), 975 (Russian) 1978. CODEN: ELKKAX. ISSN: 0424-8570. DOCUMENT TYPE: Journal CA Section: 72 (Electrochemistry) Section cross-reference(s): 22 The cathodic redn. of o-, m-, and p-isomers of nitroaniline was studied on a Au amalgamated electrode in acid solns. The main redn. product of m-nitroaniline [99-09-2] is m-(hydroxyamino)aniline [67591-44-0]; however, the formation of m-phenylenediamine [108-45-2] and 2,4-diaminophenol [95-86-3] was obsd. The final products of the redn. of o-nitroaniline [88-74-4] were unstable o-(hydroxyamino)aniline [43019-70-1] and o-phenylenediamine [95-54-5]. The cathodic redn. of p-nitroaniline [100-01-6] and phenylenediamine [25265-76-3] proceeds with the formation of an intermediate product having the structure of a dihydrobenzene deriv., which forms through addn. of 6 electrons to a mol. of the p-isomer. The half-wave potential of its oxidn. on the ring differs from that of p-phenylenediamine and does not depend on pH. No similar intermediate products were found during the redn. of m- or o-nitroaniline.