Reference

Benzenesulfonyl chlorides

Benzenesulfonyl chlorides. Moreau, Robert Cesar; Fournier, Jean Paul (Choay S. A., Fr.). Fr. 22521-37-5 which is the cas registry number is also used here. Demande FR 2338929 19 Aug 1977, 7 pp. (French). (France). CODEN: FRXXBL. CLASS: IC: C07C143-70. APPLICATION: FR 76-1685 22 Jan 1976. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) Anilines I (R = NO2, H; R1 = H, Cl, SO2NH2) were diazotized and treated with SO2 and CuCl2 catalyst to yield the resp. benzenesulfonyl chlorides II, which are intermediates for the prepn. of N-substituted benzenesulfonamides useful as anticonvulsants and antiemetics. 4-Chlorophenol was nitrated, O-methylated, reduced, N-acetylated, nitrated, and deacetylated to give 5-chloro-2-methoxy-4-nitroaniline, and the latter was diazotized and treated with SO2 and CuCl2 to give II (R = NO2, R1 = Cl). .

Benzenesulfonyl chloride

Benzenesulfonyl chloride. Blank, Heinz Ulrich (Bayer A.-G., Ger.). Ger. Offen. DE 2635279 9 Feb 1978, 15 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C07C143-70. APPLICATION: DE 76-2635279 5 Aug 1976. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) PhSO2Cl was prepd. by reaction of C6H6 with SOCl2 and ClSO3H in a manner to minimize environmental damage from by-products. Thus, 3.2 mol SOCl2 mixed with 1.6 mol ClSO3H at 50° was treated with 1.6 mol C6H6 over 4 h at 50° and the mixt. distd. to give 79% PhSO2Cl of 99.5% purity. Excess reactants were distd. and recycled; the HCl and SO2 by-products can be collected for further use.