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98-64-6

Basic Information
CAS No.: 98-64-6
Name: 4-Chlorobenzenesulfonamide
Article Data: 86
Molecular Structure:
Molecular Structure of 98-64-6 (4-Chlorobenzenesulfonamide)
Formula: C6H6ClNO2S
Molecular Weight: 191.638
Synonyms: Benzenesulfonamide,p-chloro- (6CI,7CI,8CI);4-Chlorophenylsulfonamide;ADD 55051;NSC 403674;NSC 9913;p-Chlorobenzenesulfamide;p-Chlorobenzenesulfonamide;p-Chlorophenylsulfonamide;
EINECS: 202-689-5
Density: 1.47 g/cm3
Melting Point: 140-144 °C(lit.)
Boiling Point: 342.2 °C at 760 mmHg
Flash Point: 160.8 °C
Solubility: Solubility in water
Appearance: White powder.
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 26-36-24/25
PSA: 68.54000
LogP: 2.76850
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Chemistry

Product Name: 4-Chlorobenzenesulfonamide
IUPAC NAME: 4-chlorobenzenesulfonamide
CAS: 98-64-6
EINECS: 202-689-5
Molecular Formula: C6H6ClNO2S
Molecular Weight: 191.64g/mol
Structure: 
                 
The synonyms of 4-Chlorobenzenesulfonamide(98-64-6): 4-chloro-benzenesulfonamid ; 4-Chlorophenylsulfonamide; p-Chlorobenzenesulfamide ; p-chloro-benzenesulfonamid ; p-Chlorophenylsulfonamide ;1-CHLORO-4-BENZENESULPHONAMIDE .
Melting Point: 140-144 °C(lit.)
Boiling Point: 342.2 °C at 760 mmHg
Density: 1.47 g/cm3
Appearance: Off-White Solid
Storage: Store in a cool, dry place. Keep container closed when not in use.

Uses

  Anticonvulsant against audiogenic convulsion and used as pharmaceutical intermediates

Production

Product Categories: SULFONAMIDE; Benzene derivates; Aromatics Compounds; Aromatics; Sulfur & Selenium Compounds; Sulfonamides/Sulfinamides; Organic Building Blocks; Sulfur Compounds

Toxicity Data With Reference

1.   

orl-rat LDLo:500 mg/kg

   NCNSA6    National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),20.
2.   

ipr-mus LD50:200 mg/kg

   NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .

 

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl.

Hazard Codes:
    Xi  Irritant 
Risk Statements about 4-Chlorobenzenesulfonamide(98-64-6):
    R36/37/38 Irritating to eyes, respiratory system and skin 
WARNING:
    Irritating to eyes, respiratory system and skin. Avoid ingestion and inhalation. 
Safety Statements about 4-Chlorobenzenesulfonamide(98-64-6):
    S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
    S36 Wear suitable protective clothing 
    S24/25 Avoid contact with skin and eyes

Specification

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse.