Reference

3-Acyl-2-(substituted) amino-5-halo-6-(substituted) pyrazine antimicrobial compounds, compositions and use

3-Acyl-2-(substituted) amino-5-halo-6-(substituted) pyrazine antimicrobial compounds, compositions and use. Johnston, David B. R. (Merck and Co., Inc. , USA). U.S. US 4442097 A 10 Apr 1984, 11 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A01N043-60; A01N043-84; C07D241-20; C07D413-04. NCL: 424248500. APPLICATION: US 82-453058 27 Dec 1982. 90601-53-9 which is the cas registry number of some chemical is mentioned. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 5 Acylpyrazines I (R = halo, mono- or dialkylamino, morpholino, SH, alkylthio, arylthio, alkanesulfonyl; R1 = Br, Cl; R2 = H, alkyl; R3 = H, alkyl; R4 = carboxyalkyl, esterified carboxyalkyl; or NR3R4 = morpholino, 1-piperazinyl, 4-alkyl-1-pierazinyl) were prepd., and they are useful as fungicides and bactericides (no data). Pyrazinecarboxamide was subjected to sequential dehydration, chlorination, substitution with morpholine, chlorination, and redn. with (Me2CHCH2)2AlH to give I (R = R1 = Cl, R2 = H, NR3R4 = morpholino). .

Pyrazinecarboxamide

Pyrazinecarboxamide. Kano, Saburo; Ito, Masaru; Genda, Yoshikazu (Nippon Soda Co., Ltd.; Sagami Chemical Research Center, Japan). Japan.Chemical with cas number 66505-29-1 also plays role. Kokai JP 53031682 25 Mar 1978 Showa, 4 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C07D241-24. APPLICATION: JP 76-104988 3 Sep 1976. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Title compd. (I) was prepd. by hydrolysis of II in aq. alkali in the presence of H2O2. Thus, 10 mL 30% aq. H2O2 was added to a mixt. of 5 g II and 30 mL 28% aq. NH3 10 min at -5° to 0° and kept overnight at -5° to 0° to give 90.9% I. .