Detail of > 99522-79-9
- CAS Number:
- 99522-79-9
- Name:
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl5-[(2E)-3-phenyl-2-propen-1-yl] ester
- Superlist Name:
- Pranidipine
- Formula:
- C25H24N2O6
- Molecular Structure:
![Molecular Structure of 99522-79-9 (3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl5-[(2E)-3-phenyl-2-propen-1-yl] ester)](http://www.lookchem.com/300w/2010/0625/99522-79-9.jpg)
- Synonyms:
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl(2E)-3-phenyl-2-propenyl ester (9CI);3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 3-phenyl-2-propenyl ester,(E)-;FRC 8411;OPC 13340;
- Molecular Weight:
- 448.47
- Density:
- 1.254 g/cm3
- Melting Point:
- 140-142 °C
- Boiling Point:
- 618.9 °C at 760 mmHg
- Flash Point:
- 328.1 °C
- Appearance:
- yellow solid
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- 86781-08-03,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(cyclopropylmethyl)5-ethyl ester
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- 100427-26-73,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester
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Reference
- Polymorphism of methyl (E)-3-phenyl-2-propenyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridi ne-3,5-dicarboxylate (FRC-8411)
- Polymorphism of methyl (E)-3-phenyl-2-propenyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridi ne-3,5-dicarboxylate (FRC-8411). Watanabe, Daiichi; Fukutani, Takashi; Ikawa, Hiroshi; Yamaura, Tetsuaki; Kase, Noriko; Mizutani, Hiroko (Cent. Res. Lab., Fujirebio Inc., Tokyo 192, Japan). Chem. Pharm. Bull., 34(11), 4855-8 (English) 1986. CODEN: CPBTAL. ISSN: 0009-2363. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1 Two crystal forms of FRC-8411 (I) [99522-79-9] were obtained by recrystn. from MeOH. These crystal forms were identified by using powder x-ray diffractometry, IR spectroscopy, and thermogravimetry. The m.ps. of forms I and II were 140 and 121°, resp., as shown by DSC. Forms I and II, having a similar particle size distribution, were administered orally or i.v. to spontaneously hypertensive rats. In the case of oral administration, the hypotensive action of form I was milder than that of form II and tachycardia was not obsd. after administration of form I.
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