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100859-84-5

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100859-84-5 Usage

Description

2-Chloroisonicotinamide, a derivative of isonicotinamide and a structural isomer of nicotinamide, is a chemical compound with the molecular formula C6H5ClN2O. It is a white to yellow crystalline solid, characterized by a melting point of 166-167°C. 2-CHLOROISONICOTINAMIDE serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals, and has been investigated for its potential as an anti-tuberculosis agent and in cancer treatment. Additionally, it is utilized as a building block in the production of other organic compounds.

Uses

Used in Pharmaceutical Industry:
2-Chloroisonicotinamide is used as an intermediate in the synthesis of various pharmaceuticals for its potential therapeutic applications. Its role in the development of anti-tuberculosis agents and cancer treatments highlights its importance in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloroisonicotinamide is employed as an intermediate in the production of agrochemicals, contributing to the development of effective solutions for agricultural applications.
Used in Organic Chemistry:
2-Chloroisonicotinamide is utilized as a building block in organic chemistry, enabling the synthesis of a range of organic compounds for diverse applications across various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 100859-84-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,5 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 100859-84:
(8*1)+(7*0)+(6*0)+(5*8)+(4*5)+(3*9)+(2*8)+(1*4)=115
115 % 10 = 5
So 100859-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClN2O/c7-5-3-4(6(8)10)1-2-9-5/h1-3H,(H2,8,10)

100859-84-5 Well-known Company Product Price

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  • Alfa Aesar

  • (H25769)  2-Chloropyridine-4-carboxamide, 98+%   

  • 100859-84-5

  • 1g

  • 469.0CNY

  • Detail
  • Alfa Aesar

  • (H25769)  2-Chloropyridine-4-carboxamide, 98+%   

  • 100859-84-5

  • 5g

  • 2347.0CNY

  • Detail
  • Alfa Aesar

  • (H50701)  2-Chloropyridine-4-carboxamide   

  • 100859-84-5

  • 1g

  • 767.0CNY

  • Detail
  • Aldrich

  • (L510386)  2-Chloroisonicotinamide  AldrichCPR

  • 100859-84-5

  • L510386-1G

  • 321.75CNY

  • Detail

100859-84-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloroisonicotinamide

1.2 Other means of identification

Product number -
Other names 2-chloropyridine-4-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100859-84-5 SDS

100859-84-5Relevant articles and documents

Cs2CO3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

Sahnoun, Sophian,Messaoudi, Samir,Peyrat, Jean-Fran?ois,Brion, Jean-Daniel,Alami, Mouad

, p. 2860 - 2863 (2012)

An efficient hydration reaction of various (hetero)aryl nitriles using Cs2CO3 in pyrrolidinone is described. This new metal-free protocol proved to be highly effective and general to synthesize a variety of (hetero)aryl amides.

Efficient and selective nitrile hydration reactions in water catalyzed by an unexpected dimethylsulfinyl anion generated in situ from CsOH and DMSO

Chen, Haonan,Dai, Wujie,Chen, Yi,Xu, Qing,Chen, Jianhui,Yu, Lei,Zhao, Yajuan,Ye, Mingde,Pan, Yuanjiang

, p. 2136 - 2141 (2014)

Unexpected dimethylsulfinyl anions (I), generated in situ from the superbase system CsOH-DMSO, was found to be a highly active catalyst for controllable nitrile hydration reactions in water, which selectively afforded the versatile amides via interesting Cs-activated I-catalyzed direct and indirect hydration mechanisms involving an O-transfer process from DMSO onto the nitriles. the Partner Organisations 2014.

A pyridine amide synthetic method of compound

-

Paragraph 0040; 0041, (2019/02/02)

The invention discloses a method for synthesizing a pyridine-amide compound. The method comprises the steps of carrying out hydrolysis on a pyridine cyanogen compound shown by a formula II as a starting material in water as a solvent in the presence of an ETS-10 molecular sieve as a catalyst, heating to 100-150 DEG C, reacting until the reaction, which is tracked and detected by virtue of TLC (Thin-Layer Chromatography), is completed and carrying out post-treatment on the reaction solution to obtain the pyridine-amide compound represented by the formula I. According to the method disclosed by the invention, the ETS-10 molecular sieve is taken as a catalyst to carry out hydrolysis on pyridine cyanogen to obtain a single pyridine-amide product, the conversion rate is 100%, the yield is above 95% and the catalyst can be repeatedly used for at least 5 times.

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