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102396-29-2

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102396-29-2 Usage

Description

6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine, also known as GDC-0349, is a pyrimidine derivative with potential therapeutic applications. It is a chemical compound that has been studied for its potential as a kinase inhibitor for the treatment of cancer. GDC-0349 is designed to inhibit the activity of specific kinases involved in cancer cell proliferation and survival, making it a promising candidate for cancer treatment.

Uses

Used in Oncology:
6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine is used as a kinase inhibitor for the treatment of cancer. It targets specific kinases involved in cancer cell proliferation and survival, potentially leading to the suppression of tumor growth and improved treatment outcomes for cancer patients.
Used in Combination Cancer Therapies:
6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine may be used in combination with other cancer therapies to enhance treatment efficacy. Its potential synergistic effects with conventional chemotherapeutic drugs could improve chemo-sensitivity and overall outcomes in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 102396-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,3,9 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 102396-29:
(8*1)+(7*0)+(6*2)+(5*3)+(4*9)+(3*6)+(2*2)+(1*9)=102
102 % 10 = 2
So 102396-29-2 is a valid CAS Registry Number.

102396-29-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-chloro-5-methyl-2-piperazin-1-yl-N-propan-2-ylpyrimidin-4-amine

1.2 Other means of identification

Product number -
Other names 2-piperazino-4-isopropylamino-5-methyl-6-chloropyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:102396-29-2 SDS

102396-29-2Downstream Products

102396-29-2Relevant articles and documents

4-Amino-6-chloro-2-piperazinopyrimidines with selective affinity for α2-adrenoceptors

Gueremy,Audiau,Renault,Benavides,Uzan,Le Fur

, p. 1394 - 1398 (2007/10/02)

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