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103539-32-8

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103539-32-8 Usage

General Description

METHYL (R)-AZIRIDINE-2-CARBOXYLATE is a chemical compound that belongs to the class of aziridines, which are three-membered heterocycles containing a nitrogen atom. It is a chiral compound, meaning it has a non-superimposable mirror image, and the (R)- designation indicates that it has a specific spatial arrangement of its atoms. METHYL (R)-AZIRIDINE-2-CARBOXYLATE is commonly used as a intermediate or building block in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and reactivity make it a valuable tool in organic synthesis, and it has been the subject of research for its potential applications in medicinal chemistry and material science.

Check Digit Verification of cas no

The CAS Registry Mumber 103539-32-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,5,3 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 103539-32:
(8*1)+(7*0)+(6*3)+(5*5)+(4*3)+(3*9)+(2*3)+(1*2)=98
98 % 10 = 8
So 103539-32-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H7NO2/c1-7-4(6)3-2-5-3/h3,5H,2H2,1H3/t3-/m1/s1

103539-32-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (2R)-aziridine-2-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103539-32-8 SDS

103539-32-8Relevant articles and documents

Synthesis of the suicide substrate D-propargylglycine stereospecifically labelled with deuterium and investigation of its oxidation by D-amino acid oxidase

Church, Nicola J.,Young, Douglas W.

, p. 1475 - 1482 (1998)

Stereospecifically deuteriated samples of D-propargylglycine 1 have been prepared by reaction of the labelled Pmc-protected aziridine free acids 22 with a lithium acetylide followed by deprotection. These samples have been used to show that D-amino acid oxidase, in converting D-propargylglycine to the lactone 5, deprotonates C-3 in a non-stereospecific manner. This strongly supports the idea that non-enzymic deprotonation is a key step in the formation of this compound.

COVALENT RAS INHIBITORS AND USES THEREOF

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Page/Page column 255, (2021/06/04)

The disclosure features compounds, or pharmaceutically acceptable salts thereof, alone and in combination with other therapeutic agents, pharmaceutical compositions, and protein conjugates thereof, capable of modulating biological processes including Ras, and their uses in the treatment of cancers.

Aryl substituted aminotetrahydropyran compound and use thereof

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Paragraph 0368; 0374; 0375; 0376, (2019/07/04)

The invention relates to an aryl substituted aminotetrahydropyran compound and use thereof, and further relates to a pharmaceutical composition comprising the compound. The compound or pharmaceuticalcomposition provided by the invention can be used as a dipeptidyl peptidase-IV (DPP-IV) inhibitor.

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