104223-90-7Relevant articles and documents
JANUS-TYPE ISOPROPYL GROUPS REVEALED BY 1H-NMR SPECTRA OF ALKYLPYRIDINES WITH LANTHANIDE SHIFT REAGENTS (LSR)
Uncuta, Cornelia,Balaban, Teodor-Silviu,Gheorghiu, Mircea D.,Stanescu, Ligia,Petride, Aurica,Balaban, Alexandru T.
, p. 4673 - 4676 (2007/10/02)
Two isomeric pyridines were designed and prepared : 2-isopropyl-4,5,6-trimethyl- (3) and 2-isopropyl-3,4,6-trimethyl-pyridine (7) ; the latter, with a buttressed isopropyl, leads to much lower induced shifts by Eu(dpm)3 and Pr(dpm)3 than the former, owing to the conformation in which the Janus-type iPr group shows to the LSR a t-butyl-like face.