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104373-77-5

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104373-77-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 104373-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,3,7 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 104373-77:
(8*1)+(7*0)+(6*4)+(5*3)+(4*7)+(3*3)+(2*7)+(1*7)=105
105 % 10 = 5
So 104373-77-5 is a valid CAS Registry Number.

104373-77-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(4-propan-2-ylsulfanylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propanamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104373-77-5 SDS

104373-77-5Downstream Products

104373-77-5Relevant articles and documents

1-(2-Pyridinyl)piperazine Derivatives with Antianaphylactic, Antibronchospastic, and Mast Cell Stabilizing Activities

Catto, Alberto,Motta, Gianni,Tajana, Alberto,Cazzulani, Pietro,Nardi, Dante,Leonardi, Amedeo

, p. 13 - 19 (2007/10/02)

New 1-(2-pyridinyl)piperazine derivatives were synthesized and tested as inhibitors of the reaginic passive cutaneous anaphylaxis in the rat (PCA), of the histamine-induced bronchospasm in the guinea pig, and of the rat mesenteric mast cell degranulation induced by compound 48/80.On the basis of test results, a series of N-(substituted phenyl)-ω-alkanamides were prepared.The nature of substituents at the anilide ring strongly influenced mast cell stabilizing activity, whereas it was less determining in the case of the other two tests.No clear correlation between the most common physicochemical parameters (?, ?, Vw volume) of substituents and activity could be detected.With regard to the position of substituents at the anilide ring, the rank order of potency, in the PCA and bronchoconstriction tests, was para > meta > ortho.Introduction of substituents in the 1-(2-pyridinyl)piperazinyl moiety of the N-(substituted phenyl)propanamide derivatives hardly affected activity, or the effect was deleterious.Some of the new compounds exhibited a simultaneous remarkable activity in all the three assays employed.

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