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104548-79-0

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104548-79-0 Usage

Commonly known as

Dolutegravir

Type of drug

HIV-1 integrase inhibitor

Mechanism of action

Blocks integrase, preventing viral DNA integration into the host genome

Use

Treatment of HIV infection in adults and children

Efficacy

High efficacy and tolerability

Adverse effects

Headache, insomnia, gastrointestinal disturbances

Specific content

Dolutegravir is a potent and selective inhibitor of HIV-1 integrase.
It is used in combination with other antiretroviral drugs for the treatment of HIV infection.
Dolutegravir works by blocking integrase, preventing viral DNA integration into the host genome.
This medication has demonstrated high efficacy and tolerability in clinical trials.
It is considered a first-line treatment for HIV infection.
Adverse effects may include headache, insomnia, and gastrointestinal disturbances.

Check Digit Verification of cas no

The CAS Registry Mumber 104548-79-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,5,4 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 104548-79:
(8*1)+(7*0)+(6*4)+(5*5)+(4*4)+(3*8)+(2*7)+(1*9)=120
120 % 10 = 0
So 104548-79-0 is a valid CAS Registry Number.

104548-79-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-9-[(2R,6R)-6-(hydroxymethyl)-1,4-dioxan-2-yl]-3H-purin-6-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104548-79-0 SDS

104548-79-0Downstream Products

104548-79-0Relevant articles and documents

Synthesis and antiviral evaluation of 1,4-dioxane nucleoside analogues related to nucleoside dialdehydes

Prisbe

, p. 2445 - 2450 (2007/10/02)

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