105281-09-2 Usage
General Description
1-(2,5-dideoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione is a chemical compound that belongs to the class of pyrimidine nucleoside analogs. It is a synthetic nucleoside analogue that contains both iodine and fluorine substituents, making it useful for various therapeutic applications. 1-(2,5-dideoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione has potential antiviral and anticancer properties due to its ability to interfere with DNA synthesis and replication. It is commonly used in research and preclinical studies to investigate its efficacy in the treatment of various viral infections and cancer types. Its unique structural features make it a promising candidate for the development of novel pharmaceutical drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 105281-09-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,2,8 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 105281-09:
(8*1)+(7*0)+(6*5)+(5*2)+(4*8)+(3*1)+(2*0)+(1*9)=92
92 % 10 = 2
So 105281-09-2 is a valid CAS Registry Number.
105281-09-2Relevant articles and documents
Nucleosides. 139. Synthesis and Anticytomegalovirus and Antiherpes Simplex Virus Activity of 5'-Modified Analogues of 2'-Fluoroarabinosylpyrimidine Nucleosides
Harada, Kazuho,Matulic-Adamic, Jasenka,Price, Richard W.,Schinazi, Raymond F.,Watanabe, Kyoichi A.,Fox, Jack J.
, p. 226 - 229 (2007/10/02)
In order to determine if modification of the 5'-position reduces or abolishes the antiviral activity of 2'-fluoro-5-iodo-ara-C (FIAC), 2'-fluoro-5-iodo-ara-U (FIAU), or 2'-fluoro-5-methyl-ara-U (FMAU) against human cytomegalovirus (HCMV) and herpes simple
