105281-19-4 Usage
General Description
1-(2-deoxy-2-fluoro-5-thio-beta-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione is a chemical compound that belongs to the class of pyrimidine nucleoside analogs. It is a modified version of the natural nucleoside deoxythymidine, with a fluorine atom and a thiol group added to the sugar moiety. This modified nucleoside has been of interest in the development of antiviral and anticancer drugs, as it can inhibit the replication of certain viruses and cancer cells by interfering with their DNA synthesis. Research on this compound has shown promising results in inhibiting the growth of cancer cells and viruses, making it a potential candidate for the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 105281-19-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,2,8 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 105281-19:
(8*1)+(7*0)+(6*5)+(5*2)+(4*8)+(3*1)+(2*1)+(1*9)=94
94 % 10 = 4
So 105281-19-4 is a valid CAS Registry Number.
105281-19-4Relevant articles and documents
Nucleosides. 139. Synthesis and Anticytomegalovirus and Antiherpes Simplex Virus Activity of 5'-Modified Analogues of 2'-Fluoroarabinosylpyrimidine Nucleosides
Harada, Kazuho,Matulic-Adamic, Jasenka,Price, Richard W.,Schinazi, Raymond F.,Watanabe, Kyoichi A.,Fox, Jack J.
, p. 226 - 229 (2007/10/02)
In order to determine if modification of the 5'-position reduces or abolishes the antiviral activity of 2'-fluoro-5-iodo-ara-C (FIAC), 2'-fluoro-5-iodo-ara-U (FIAU), or 2'-fluoro-5-methyl-ara-U (FMAU) against human cytomegalovirus (HCMV) and herpes simple
