1059-14-9Relevant articles and documents
Carbon-13 Resonance Assignments of some Friedelanes and Taraxasteranes
Patra, Amarendra,Mukhopadhyay, Apurba K.,Mitra, Alok K.
, p. 166 - 168 (1981)
Carbon-13 signal assignments of taraxasteryl acetate, taraxasteryl palmitate, taraxasterol and epi-friedenyl acetate are reported.Some signal assignments of the friedelanones, reported recently by others, are inconsistent and require revision.
Antispasmodic and spasmogenic effects of Scolymus hispanicus and taraxasteryl acetate on isolated ileum preparations
Kirimer, Nes'E,Tunalier, Zeynep,Baser, K. Huesnue Can,Cingi, Ipek
, p. 556 - 558 (1997)
Taraxasteryl acetate (1) was identified as the major triterpenoid of the ethanolic extract of the root bark of Scolymus hispanicus L. Antispasmodic and spasmogenic effects of the ethanolic extract, its fractions, taraxasteryl acetate, and a fluid extract of this plant were tested on isolated rat ileum preparations. The strong biphasic responses observed suggested a possible lithuretic activity of the compounds and the fractions tested.
Terpenoids in four Inula species from Bulgaria
Aneva, Ina,Ivanova, Victoria,Staleva, Plamena,Todorova, Milka,Trendafilova, Antoaneta
, p. 1229 - 1240 (2022/02/16)
Phytochemical study of the chloroform extract of the aerial parts of Inula germanica L., I. ensifolia L., I. conyza (Griess.) DC. and I. salicina L. led to the identification of 33 terpenoids. β- and α-amyrin, lupeol, taraxasterol, ψ-taraxasterol and their 3-O-acetates and 3-O-palmitates were identified by GC/MS. In addition, the structures of 3-O-palmitates of mainaladiol, arnidiol, faradiol and 16-hydroxylupeol were confirmed by NMR. ent-Kaur-16-en-19- -oic acid and its 15α-(3-methylpentanoyloxy) and 15α-(3-methylbutanoyloxy) derivatives were isolated from I. conyza. Ten closely related sesquiterpene lactones (germacranolides and melampolides) were found in I. germanica and their structural identification was performed by spectral analyses. I. ensifolia and I. salicina were free of sesquiterpene lactones and diterpenoids. All triterpenoids and diterpenoids, grazielia acid, desacetylovatifolin and 8-(2-methylbutanoyloxy)- 1(10),4,11(13)-germacrutrien-6,12-olide-14-oic acid are described for the first time in the studied species. The principal component analysis was used to find a relationship between the investigated up to now Inula species, growing in Bulgaria.
Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol
Segura, Michael J. R.,Meyer, Michelle M.,Matsuda, Seiichi P. T.
, p. 2257 - 2259 (2007/10/03)
lupeol lupeol, germanicol, synthase β-amyrin, taxasterol, oxidosqualene → ψ-taraxasterol, and 3,20-dihydroxylupane The Arabidopsis thaliana LUP1 gene encodes an enzyme that converts oxidosqualene to pentacyclic triterpenes. Lupeol and β-amyrin were previously reported as LUP1 products. Further investigation described here uncovered the additional products germanicol, taraxasterol, ψ-taraxasterol, and 3,20-dihydroxylupane. These results suggest that the 80 known C30H50O compounds that are structurally consistent with being oxidosqualene cyclase products may be derived from fewer than 80 enzymes and that some C30H52O2 compounds may be direct cyclization products of oxidosqualene.