1065-31-2 Usage
Uses
CoQ6 has been used: as an internal standard for the liquid-chromatography mass-spectrometry for the quantification of CoQ6to determine its effect on peroxisome proliferator-activated receptor (PPAR)in reversed-phase high pressure liquid chromatography to quantify yeast quinones
Definition
ChEBI: A ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.
General Description
Coenzyme Q6 (CoQ6) is also known as ubiquinone-30 in Saccharomyces cerevisiae. It is a flavoprotein that utilizes flavin adenine dinucleotide (FAD) as a co-factor for the synthesis of coenzyme Q. It is composed of three conserved regions- a FAD/ nicotinamide adenine dinucleotide (NAD) + hydrogen (H) (NADH) binding motif, an adenine di phosphate (ADP) binding motif and a consensus sequence, that binds to the ribityl moiety of FAD.
Biochem/physiol Actions
Coenzyme Q6 (CoQ6) in the plasma membrane of Saccharomyces cerevisiae is involved in the ascorbate stabilization at the plasma membrane.
Check Digit Verification of cas no
The CAS Registry Mumber 1065-31-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,6 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1065-31:
(6*1)+(5*0)+(4*6)+(3*5)+(2*3)+(1*1)=52
52 % 10 = 2
So 1065-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C39H58O4/c1-28(2)16-11-17-29(3)18-12-19-30(4)20-13-21-31(5)22-14-23-32(6)24-15-25-33(7)26-27-35-34(8)36(40)38(42-9)39(43-10)37(35)41/h16,18,20,22,24,26H,11-15,17,19,21,23,25,27H2,1-10H3/b29-18+,30-20+,31-22+,32-24+,33-26+
1065-31-2Relevant articles and documents
A convergent approach to coenzyme Q
Lipshutz, Bruce H.,Bulow, Gerd,Fernandez-Lazaro, Fernando,Kim, Sung-Kyu,Lowe, Richard,Mollard, Paul,Stevens, Kirk L.
, p. 11664 - 11673 (2007/10/03)
Syntheses of coenzyme Q3-8 are described, as well as related systems such as plastoquinone-5. Preparation of the higher homologues of the ubiquinones relies on two new conjunctive reagents, or "linchpins", each of which ultimately corresponds to two or three prenyl units. These allow for attachment of a polyprenyl halide at one end, followed by a Ni(0)-catalyzed cross-coupling at the other terminus with a chloromethylated p-quinone.