107263-89-8Relevant articles and documents
HETEROCYCLIC COMPOUNDS AND USES THEREOF
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Paragraph 00655; 00659; 00709, (2015/04/22)
Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
NOVEL HETEROCYCLIC DERIVATIVES AS M-GLU5 ANTAGONISTS
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Page/Page column 38, (2009/03/07)
This invention relates to novel heterocyclic compounds having selective affinity for the mGlu5 subtype of metabotropic receptors, pharmaceutical compositions thereof and uses for such compounds and compositions in the treatment of lower urinary tract diso
Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: Modification of the side chain
Paterson, Ian,Menche, Dirk,Hakansson, Anders E.,Longstaff, Adrian,Wong, David,Barasoain, Isabel,Buey, Ruben M.,Diaz, J. Fernando
, p. 2243 - 2247 (2007/10/03)
Novel, simplified analogues of the microtubule-stabilizing anticancer agent laulimalide, including the first derivatives with unnatural side chains, were designed by molecular modelling, synthesized by a late-stage diversification strategy, and evaluated in vitro for growth inhibition of human ovarian carcinoma cell lines (A2780, A2780/AD10).