108885-68-3 Usage
Description
Taccalonolide A, a natural product derived from plants of the genus Tacca, is a potent microtubule-stabilizing agent with significant anticancer properties. It induces microtubule polymerization and stabilizes microtubules, resulting in cell cycle arrest and apoptosis in cancer cells. Taccalonolide A also demonstrates activity against multidrug-resistant cancer cells, positioning it as a promising candidate for the development of new anticancer drugs.
Uses
Used in Pharmaceutical Industry:
Taccalonolide A is used as an anticancer agent for its ability to induce microtubule polymerization and stabilize microtubules, leading to cell cycle arrest and apoptosis in cancer cells. It is particularly effective against various forms of cancer, including breast, lung, and ovarian cancer.
Used in Cancer Research:
Taccalonolide A is utilized as a research tool for studying the mechanisms of microtubule dynamics and their role in cancer cell proliferation and survival. Its activity against multidrug-resistant cancer cells makes it a valuable compound for investigating novel therapeutic strategies to overcome drug resistance in cancer treatment.
Used in Drug Development:
Taccalonolide A serves as a lead compound in the development of new anticancer drugs. Its potent microtubule-stabilizing properties and activity against multidrug-resistant cancer cells make it a promising starting point for designing and optimizing more effective and targeted cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 108885-68-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,8,8 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 108885-68:
(8*1)+(7*0)+(6*8)+(5*8)+(4*8)+(3*5)+(2*6)+(1*8)=163
163 % 10 = 3
So 108885-68-3 is a valid CAS Registry Number.
108885-68-3Relevant articles and documents
TACCALONOLIDE MICROTUBULE STABILIZERS
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Paragraph 00390, (2018/07/05)
The present disclosure relates to the fields of medicine and pharmaceuticals. In particular, the invention relates to the identification of epoxytaccalonolide microtubule stabilizers for use in inhibiting cell proliferation and disrupting normal cellular microtubule processes leading to cell death. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
