110677-79-7 Usage
Molecular Structure
1-hydroxy-N-(3-methoxyphenyl)naphthalene-2-carboxamide has a complex molecular structure, which includes a naphthalene derivative, a hydroxy group, a carboxamide group, and a methoxyphenyl group.
Derivative of Naphthalene
The compound is derived from naphthalene, which is a polycyclic aromatic hydrocarbon consisting of two fused benzene rings.
Hydroxy Group
The presence of a hydroxy group (-OH) in the compound contributes to its polarity and solubility in water, which can affect its biological activity and interactions with other molecules.
Carboxamide Group
The carboxamide group (-CONH2) is a functional group present in the compound, which can participate in hydrogen bonding and coordinate with metal ions, influencing its potential therapeutic properties.
Therapeutic Properties
1-hydroxy-N-(3-methoxyphenyl)naphthalene-2-carboxamide has potential therapeutic properties, such as anti-inflammatory and analgesic effects, making it a valuable compound in pharmaceutical development.
Enzyme Inhibition
The compound is known to inhibit certain enzymes, which may have applications in drug design and development, as it can potentially be used as a lead compound for the development of new drugs targeting specific enzymes.
Scientific Research
Due to its unique structure and properties, 1-hydroxy-N-(3-methoxyphenyl)naphthalene-2-carboxamide is often used in scientific research to study its interactions with other molecules and its potential applications in various fields.
Pharmaceutical Development
The compound's potential therapeutic properties and enzyme inhibition capabilities make it a valuable asset in pharmaceutical development, as it can be further studied and modified to create new drugs for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 110677-79-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,6,7 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 110677-79:
(8*1)+(7*1)+(6*0)+(5*6)+(4*7)+(3*7)+(2*7)+(1*9)=117
117 % 10 = 7
So 110677-79-7 is a valid CAS Registry Number.
110677-79-7Relevant articles and documents
Investigation of hydro-lipophilic properties of n-alkoxyphenylhydroxynaphthalenecarboxamides ?
Kapustikova, Iva,Bak, Andrzej,Gonec, Tomas,Kos, Jiri,Kozik, Violetta,Jampilek, Josef
, (2018/07/10)
The evaluation of the lipophilic characteristics of biologically active agents is indispensable for the rational design of ADMET-tailored structure–activity models. N-Alkoxy-3-hydroxynaphthalene-2-carboxanilides, N-alkoxy-1-hydroxynaphthalene-2-carboxanilides, and N-alkoxy-2-hydroxynaphthalene-1-carboxanilides were recently reported as a series of compounds with antimycobacterial, antibacterial, and herbicidal activity. As it was found that the lipophilicity of these biologically active agents determines their activity, the hydro-lipophilic properties of all three series were investigated in this study. All 57 anilides were analyzed using the reversed-phase high-performance liquid chromatography method for the measurement of lipophilicity. The procedure was performed under isocratic conditions with methanol as an organic modifier in the mobile phase using an end-capped non-polar C18 stationary reversed-phase column. In the present study, a range of software lipophilicity predictors for the estimation of clogP values of a set of N-alkoxyphenylhydroxynaphthalenecarboxamides was employed and subsequently cross-compared with experimental parameters. Thus, the empirical values of lipophilicity (logk) and the distributive parameters (π) were compared with the corresponding in silico characteristics that were calculated using alternative methods for deducing the lipophilic features. To scrutinize (dis)similarities between the derivatives, a PCA procedure was applied to visualize the major differences in the performance of molecules with respect to their lipophilic profile, molecular weight, and violations of Lipinski’s Rule of Five.
