110927-03-2 Usage
Description
3,4-Dihydro-5-methoxy-2H-1-Benzopyran-3-amine, also known as 5-MeO-DHBP, is a chemical compound belonging to the benzopyranamine class. It is a derivative of the natural product avobenzone and serves as a building block in the synthesis of pharmaceuticals and other organic compounds. With potential pharmacological properties, particularly in neuropharmacology, 5-MeO-DHBP has been studied for its role in modulating serotonin receptors, showing promise as a therapeutic agent for conditions such as depression and anxiety. Furthermore, it has been explored as a precursor in the synthesis of novel psychoactive substances.
Uses
Used in Pharmaceutical Synthesis:
3,4-Dihydro-5-methoxy-2H-1-Benzopyran-3-amine is used as a building block in the synthesis of pharmaceuticals for its versatile chemical structure and potential to contribute to the development of new therapeutic agents.
Used in Neuropharmacology Research:
In the field of neuropharmacology, 3,4-Dihydro-5-methoxy-2H-1-Benzopyran-3-amine is used as a research compound to study its potential role in modulating serotonin receptors, which is crucial for understanding its effects on conditions like depression and anxiety.
Used in the Development of Novel Psychoactive Substances:
3,4-Dihydro-5-methoxy-2H-1-Benzopyran-3-amine is also used as a precursor in the synthesis of novel psychoactive substances, indicating its potential in creating new compounds with various psychological effects.
Check Digit Verification of cas no
The CAS Registry Mumber 110927-03-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,9,2 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 110927-03:
(8*1)+(7*1)+(6*0)+(5*9)+(4*2)+(3*7)+(2*0)+(1*3)=92
92 % 10 = 2
So 110927-03-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO2/c1-12-9-3-2-4-10-8(9)5-7(11)6-13-10/h2-4,7H,5-6,11H2,1H3
110927-03-2Relevant articles and documents
Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2
Hatzenbuhler, Nicole T.,Baudy, Reinhardt,Evrard, Deborah A.,Failli, Amedeo,Harrison, Boyd L.,Lenicek, Steven,Mewshaw, Richard E.,Saab, Annmarie,Shah, Uresh,Sze, Jean,Zhang, Minsheng,Zhou, Dahui,Chlenov, Michael,Kagan, Michael,Golembieski, Jeannette,Hornby, Geoffrey,Lai, Margaret,Smith, Deborah L.,Sullivan, Kelly M.,Schechter, Lee E.,Andree, Terrance H.
scheme or table, p. 6980 - 7004 (2009/11/30)
Novel compounds combining a 5-HT1A moiety (3-aminochroman scaffold) and a 5-HT transporter (indole analogues) linked through a common basic nitrogen via an alkyl chain attached at the 1- or 3-position of the indole were evaluated for dual affin
Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrans: New synthesis and dopaminergic activity
Al Neirabeyeh,Reynaud,Podona,Ou,Perdicakis,Coudert,Guillaumet,Pichat,Gharib,Sarda
, p. 497 - 504 (2007/10/02)
The synthesis of methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran from readily available or commercial o-hydroxybenzaldehydes is described in six steps. The enantiomers of 8-hydroxy-3,4-dihydro-3-(di-n-propyl-amino)-2H-1-benzopyran 1b have been resolved. It is shown that the compound (-)-1b is a mroe selective D-2 agonist, compared to apomorphine.