111150-07-3 Usage
Description
FOR-MET-LEU-PNA, also known as N-formyl-methionyl-leucyl-phenylalaninamide, is a synthetic peptide compound that serves as a substrate for various biological and pharmaceutical applications. It is designed to mimic the structure of natural peptides, allowing researchers to study the activity and function of specific enzymes and proteins.
Source:
FOR-MET-LEU-PNA is synthesized in a laboratory setting, typically through the stepwise addition of amino acids to a growing peptide chain using solid-phase peptide synthesis techniques.
Production Methods:
The production of FOR-MET-LEU-PNA involves the stepwise addition of amino acids (methionine, leucine, and phenylalanine) to a growing peptide chain, starting with the N-formyl group attached to the initial methionine residue. This process is carried out using solid-phase peptide synthesis, which allows for the efficient and controlled synthesis of the desired peptide sequence.
Uses
Used in Pharmaceutical Research:
FOR-MET-LEU-PNA is used as a substrate in the characterization of peptide deformylase, an enzyme that plays a crucial role in the maturation of proteins in various organisms, including the malaria-causing Plasmodium falciparum. By studying the interaction between FOR-MET-LEU-PNA and peptide deformylase, researchers can gain insights into the enzyme's function and potentially develop novel therapeutic strategies for treating malaria and other diseases.
Used in Enzyme Inhibition Studies:
FOR-MET-LEU-PNA can also be employed in the study of enzyme inhibition, particularly for enzymes that specifically target formylated peptides. By using this synthetic peptide as a substrate, researchers can investigate the potency and selectivity of potential inhibitors, which may lead to the development of new drugs targeting these enzymes for various therapeutic applications.
Used in Drug Design and Development:
The unique structure of FOR-MET-LEU-PNA makes it a valuable tool in the design and development of new drugs targeting specific enzymes and proteins. By understanding how this synthetic peptide interacts with its target, researchers can design more effective and selective drug candidates that can modulate the activity of these targets for therapeutic benefit.
Check Digit Verification of cas no
The CAS Registry Mumber 111150-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,1,5 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 111150-07:
(8*1)+(7*1)+(6*1)+(5*1)+(4*5)+(3*0)+(2*0)+(1*7)=53
53 % 10 = 3
So 111150-07-3 is a valid CAS Registry Number.
