111964-70-6Relevant articles and documents
One step synthesis of optically active diazabicyclo-[3.3.0] octanones or diazabicyclo [4.3.0] nonanones by asymmetric conjugate addition of cyclic hydrazine
Seki, Chigusa,Hirama, Masafumi,Sato, Takeshi,Takeda, Saya,Kohari, Yoshihito,Ishigaki, Kazuhiro,Ohuchi, Masafumi,Yokoi, Kiyoshi,Nakano, Hiroto,Uwai, Koji,Takano, Nobuhiro,Umemura, Kazuyuki,Matsuyama, Haruo
experimental part, p. 1045 - 1052 (2012/07/28)
Asymmetric conjugate addition-cyclization of lithium amide of 6-membered hydrazine 4, piperidazine, (or 5-membered hydrazine 6, pyrazolidine) to N-(E)-cinnamoyl-(1S)-2,10-camphorsultam (1S)-3 afforded β-amino acid derivative (S)-1 {or (S)-2} for the synthesis of polyamine alkaloids in good yield with good stereoselectivity (up to 86% ee).
Chiral vinyl sulfoxides as useful reagents for the synthesis of β-amino acid derivatives
Matsuyama, Haruo,Itoh, Nobuhiro,Yoshida, Masato,Iyoda, Masahiko
, p. 475 - 476 (2007/10/03)
(S)- and (R)-β-amino acid derivatives were synthesized by the asymmetric conjugate addition of ammonia and piperidazine to t-butyl (E)-2-[(R)-and (S)-p-tolylsulfinyl]cinnamates, respectively.
Diastereoselective Conjugate Addition of Cyclic Hydrazine to Optically Active Vinyl Sulfoxide. A Novel Synthesis of Optically Active Azalactams
Matsuyama, Haruo,Itoh, Nobuhiro,Kamigata, Nobumasa
, p. 1547 - 1550 (2007/10/02)
Optically active (R)-(+)-1,5-diaza-4-phenylbicyclononan-2-one (5) was prepared in high optical purity by diastereoselective conjugate addition of piperidazine to optically active (E)-(S)-1-(methoxycarbonyl)-2-phenylvinyl p-tolyl sulfoxide, followed
