112190-16-6Relevant articles and documents
Inhibitors of the Protease from Human Immunodeficiency Virus: Design and Modeling of a Compound Containing a Dihydroxyethylene Isostere Insert with High Binding Affinity and Effective Antiviral Activity
Thaisrivongs, Suvit,Tomasselli, Alfredo G.,Moon, Joseph B.,Hui, John,McQuade, Thomas J.,et al.
, p. 2344 - 2356 (2007/10/02)
The peptidomimetic template and the dihydroxyethylene isostere insert that were applied successfully to the design of renin inhibitors have been extended to the related protease from human immunodeficiency virus (HIV).The present report describes the stru