112888-76-3 Usage
Description
Tert-Butyl 4-(2-propynylamino)benzoate is a versatile chemical compound characterized by the presence of a tert-butyl group, a benzene ring, and an amino group with a propynyl substituent. tert-Butyl 4-(2-propynylamino)benzoate is recognized for its steric hindrance provided by the tert-butyl group, which enhances the stability and solubility in nonpolar solvents. The propynylamino moiety allows for participation in a range of chemical reactions, making it a valuable intermediate in organic synthesis.
Uses
Used in Organic Synthesis:
Tert-Butyl 4-(2-propynylamino)benzoate is utilized as a building block in organic synthesis for its ability to participate in various chemical reactions, making it a key component in the creation of pharmaceuticals and agrochemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, tert-Butyl 4-(2-propynylamino)benzoate is used as a versatile intermediate for the synthesis of biologically active compounds, capitalizing on its reactivity and structural features to develop new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, tert-Butyl 4-(2-propynylamino)benzoate serves as a crucial intermediate, contributing to the development of new agrochemicals that can enhance crop protection and yield.
Used in Material Science:
Tert-Butyl 4-(2-propynylamino)benzoate may also find applications in material science, where it could be employed as a precursor for the synthesis of new materials with unique properties, owing to its structural attributes and synthetic potential.
Used as a Precursor in Chemical Research:
In the realm of chemical research, tert-Butyl 4-(2-propynylamino)benzoate is used as a precursor to explore novel synthetic pathways and discover new compounds with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 112888-76-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,8,8 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 112888-76:
(8*1)+(7*1)+(6*2)+(5*8)+(4*8)+(3*8)+(2*7)+(1*6)=143
143 % 10 = 3
So 112888-76-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO2/c1-5-10-15-12-8-6-11(7-9-12)13(16)17-14(2,3)4/h1,6-9,15H,10H2,2-4H3
112888-76-3Relevant articles and documents
SYNTHESIS OF CYCLOPENTAQUINAZOLINES
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Page/Page column 61-62, (2012/02/05)
A method of producing 6-amino-cyclopenta[g]quinazolines, in enantiomerically enriched form, is provided. In particular, the method may be applicable to the synthesis of N-{N-{4- [N-((6S)-2-hydroxymethyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclo-penta[g]quinazolin
Quinazoline antifolate thymidylate synthase inhibitors: Replacement of glutamic acid in the C2-methyl series
Marsham,Jackman,Barker,Boyle,Pegg,Wardleworth,Kimbell,O'Connor,Calvert,Hughes
, p. 994 - 1004 (2007/10/02)
The synthesis of a series of analogues of the potent thymidylate synthase (TS) inhibitor N-[4[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N- prop-2-ynylamino]benzoyl]-L-glutamic acid (ICI 198583, 1) is described in which the glutamic acid residu
