113145-70-3

• 

• Basic information

  1. Product Name: R(-)-NIGULDIPINE HCL
  2. Synonyms: R(-)-NIGULDIPINE HCL;R(-)-NIGULDIPINE HYDROCHLORIDE (B859-35);(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-(4,4-diphenyl-1-piperidinyl)propylmethy;(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid,3-(4,4-diphenyl-1-piperidinyl)propylmethylesterhydrochloride
  3. CAS NO:113145-70-3
  4. Molecular Formula: C36H39N3O6
  5. Molecular Weight: 646.17
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 113145-70-3.mol
  9. Article Data: 1

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 729.5°C at 760 mmHg
  3. Flash Point: 395°C
  4. Appearance: pale yellow/
  5. Density: N/A
  6. Vapor Pressure: 3.9E-21mmHg at 25°C
  7. Refractive Index: N/A
  8. Storage Temp.: −20°C
  9. Solubility: methanol: soluble
  10. CAS DataBase Reference: R(-)-NIGULDIPINE HCL(CAS DataBase Reference)
  11. NIST Chemistry Reference: R(-)-NIGULDIPINE HCL(113145-70-3)
  12. EPA Substance Registry System: R(-)-NIGULDIPINE HCL(113145-70-3)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany: 3
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 113145-70-3(Hazardous Substances Data)

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113145-70-3 Suppliers

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  Cas No: 113145-70-3

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• Zhuozhou Wenxi import and Export Co., Ltd
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• (R)-(-)-Niguldipine hydrochloride

  Cas No: 113145-70-3

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• (R)-(-)-NIGULDIPINE HCL; (R)-1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRID INEDICARBOXYLIC ACID,3-(4,4-DIPHENYL-PIPERIDIN-1-YL)PROPYL METHYL ESTER HCL

  Cas No: 113145-70-3

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• Hangzhou Fandachem Co.,Ltd
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• (R)-(-)-Niguldipine hydrochloride;(R)-1,4-Dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid,3-(4,4-diphenyl-1-piperidinyl)propylMethylesterhydrochloride

  Cas No: 113145-70-3

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• Wuxi Morality Chemical Co., Ltd
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113145-70-3 Usage

Uses

(R)-(-)-Niguldipine Hydrochloride is a potent chemosensitizer in multidrug resistant cells.

Biological Activity

L-type Ca 2+ channel blocker and α 1A -adrenoceptor antagonist; less active enantiomer.

Biochem/physiol Actions

Less active enantiomer

Check Digit Verification of cas no

The CAS Registry Mumber 113145-70-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,1,4 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 113145-70:
(8*1)+(7*1)+(6*3)+(5*1)+(4*4)+(3*5)+(2*7)+(1*0)=83
83 % 10 = 3
So 113145-70-3 is a valid CAS Registry Number.

InChI:InChI=1/C36H39N3O6.ClH/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29;/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3;1H/t33-;/m1./s1

113145-70-3 Well-known Company Product Price

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• Aldrich

• (N162)  R-(−)-Niguldipinehydrochloride  

• 113145-70-3

• N162-5MG

• 2,781.09CNY

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113145-70-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	5-O-(4,4-diphenylpiperidin-1-yl) 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-propyl-4H-pyridine-3,5-dicarboxylate,hydrochloride

1.2 Other means of identification

Product number	-
Other names	3,5-Pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester,monohydrochloride,(4R)-(9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:113145-70-3 SDS

113145-70-3Upstream product

113145-70-3Downstream Products

113145-70-3Relevant articles and documents

Optically-active 1,4-dihydropyridine

-

, (2008/06/13)

The invention relates to 3-methyl-5-[3-(4,4-diphenylpiperid-1-yl)-propyl] (+)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-piperidine-3,5-dicarboxylate and its salts and to their preparation and use.

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