113973-31-2 Usage
General Description
(Z)-Akuammidine is a naturally occurring alkaloid found in the stem bark extracts of the plant Picralima nitida. It has been studied for its potential medicinal properties, including its antiplasmodial and antinociceptive effects. As an antiplasmodial agent, (Z)-Akuammidine has shown promising results in inhibiting the growth of Plasmodium falciparum, the parasite responsible for causing malaria. Additionally, it has demonstrated antinociceptive properties, indicating its potential use as an analgesic. Further research is needed to fully understand the pharmacological activities and potential therapeutic applications of (Z)-Akuammidine.
Check Digit Verification of cas no
The CAS Registry Mumber 113973-31-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,9,7 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 113973-31:
(8*1)+(7*1)+(6*3)+(5*9)+(4*7)+(3*3)+(2*3)+(1*1)=122
122 % 10 = 2
So 113973-31-2 is a valid CAS Registry Number.
113973-31-2Relevant articles and documents
CHARACTERISTICS OF VELLOSIMINE REDUCTASE, A SPECIFIC ENZYME INVOLVED IN THE BIOSYNTHESIS OF THE RAUWOLFIA ALKALOID SARPAGINE
Pfitzner, Artur,Krausch, Brigitte,Stoeckigt, Joachim
, p. 1691 - 1700 (2007/10/02)
A plant enzyme - vellosimine reductase - has been isolated from Rauwolfia cell suspension cultures.This new enzyme has been purified (110-fold) and characterized.The reductase is a specific enzyme of the sarpagine pathway catalyzing the NADPH dependent conversion of vellosimine into 10-deoxysarpagine.The latter alkaloid is the immediate biogenetic precursor of sarpagine as shown by its high in vivo incorporation rate (86percent) into sarpagine.
