113975-33-0 Usage
General Description
N-(3-IODO-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE is a chemical compound with the molecular formula C12H15IN2O. It is a derivative of 2,2-dimethyl-propionamide, containing a pyridine ring with an iodine atom at the 3-position. N-(3-IODO-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE is commonly used as an intermediate in the synthesis of various pharmaceuticals and other organic compounds. It may also have potential applications in the field of medicinal chemistry and drug development due to its structural features. Additionally, it is important to handle this compound with care and follow proper safety protocols, as it may pose health and environmental risks if mishandled.
Check Digit Verification of cas no
The CAS Registry Mumber 113975-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,9,7 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 113975-33:
(8*1)+(7*1)+(6*3)+(5*9)+(4*7)+(3*5)+(2*3)+(1*3)=130
130 % 10 = 0
So 113975-33-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H13IN2O/c1-10(2,3)9(14)13-8-4-5-12-6-7(8)11/h4-6H,1-3H3,(H,12,13,14)
113975-33-0Relevant articles and documents
Metalation/SRN1 Coupling in Heterocyclic Synthesis. A Convenient Methodology for Ring Functionalization
Estel, L.,Marsais, F.,Queguiner, G.
, p. 2740 - 2744 (1988)
Lithiation, iodination, and fluorine substitution on 2-fluoropyridine gave 2-substituted 3-iodopyridines, which were further subjected to iodine SRN1 substitution by carbon, sulfur, and phosphorus nucleophiles.Iodine substitution by enolates on 2-amino-3-iodopyridines afforded ketones, which were further cyclized to various 1,2-disubstituted pyrrolopyridines. 2-Amino-3-iodo-, 3-amino-4-iodo, and 4-amino-3-iodopyridines were prepared by directed metalation of 2-, 3-, and 4-(pivaloylamino)pyridines.Substitution of iodine by enolates under SRN1 conditions and acidic cyclization led to various 2-substituted pyrrolo, --, and -pyridines in high yields.
