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113981-44-5

113981-44-5

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113981-44-5 Usage

General Description

Cefozopran hydrochloride is a type of cephalosporin antibiotic used in medical treatments. It is known for its broad spectrum of antimicrobial activity and typically targets a wide range of bacteria, making it particularly effective for fighting different types of infections. The compound, like other cephalosporins, works by disrupting the synthesis of the bacterial cell wall, leading to the cell's death. Given its role, it's frequently used in the healthcare setting, although the use must be carefully monitored due to potential resistance and side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 113981-44-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,9,8 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 113981-44:
(8*1)+(7*1)+(6*3)+(5*9)+(4*8)+(3*1)+(2*4)+(1*4)=125
125 % 10 = 5
So 113981-44-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H17N9O5S2.ClH/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27;/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32);1H/b24-11-;/t12-,17-;/m1./s1

113981-44-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Cefozopran HCl

1.2 Other means of identification

Product number -
Other names Czop

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:113981-44-5 SDS

113981-44-5Downstream Products

113981-44-5Relevant articles and documents

A method for preparing cefozopran hydrochloride

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Paragraph 0017; 0060; 0066, (2017/09/01)

The invention belongs to the field of a preparing method of cephalosporin, in particular to a preparing method of cefozopran hydrochloride. According to the method, an intermediate cefozopran is taken as an initial reactant to research how to prepare the cefozopran hydrochloride bulk pharmaceutical chemical which is low in water content, is low in organic solvent residue and accords with requirements in JP15 (Japanese Pharmacopeia, the 15th Edition). The invention adopts the following technical solvent: (1) the cefozopran in formula IIa reacts with hydrochloric acid to generate an Ia cefozopran hydrochloride solvate by taking an organic solvent and water as a solvent; (2) triethylamine is added dropwise into the Ia solvated cefozopran hydrochloride in a water solvent to reversely prepare the cefozopran to obtain a IIb cefozopran with a qualified residual solution; (3) HCl gas is introduced to the IIb cefozopran with the qualified residual solution to obtain the cefozopran hydrochloride with qualified water content by taking an ether solvent as a reaction solvent. The purity of the final product prepared in the technical solution is more than 99.0%, solvent residue and water content both meet standards of the Pharmacopeia and the product can be directly used for medicine preparation.

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