114059-99-3 Usage
Description
2-Aminobenzylchloride, also known as o-chlorobenzylamine, is an organic compound characterized by its chemical formula C7H8ClN. It presents as a clear, colorless to slightly yellow liquid, accompanied by a strong, unpleasant odor. 2-Aminobenzylchloride is recognized for its reactivity and versatility in undergoing various chemical transformations, making it a valuable intermediate in the synthesis of a diverse array of organic compounds, especially in the pharmaceutical and agrochemical industries.
Uses
Used in Pharmaceutical Industry:
2-Aminobenzylchloride is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its ability to participate in a range of chemical reactions allows for the creation of different medicinal agents, contributing to the development of new drugs and therapeutics.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Aminobenzylchloride serves as a building block in the production of various agrochemicals. Its reactivity is harnessed to synthesize compounds that can be used in the development of pesticides, herbicides, and other agricultural chemicals, thereby supporting crop protection and enhancement efforts.
Used in Organic Synthesis:
2-Aminobenzylchloride is utilized as a versatile reagent in organic synthesis for creating a multitude of organic compounds. Its capacity to undergo various chemical transformations makes it instrumental in the synthesis of specialty chemicals, fine chemicals, and other complex organic molecules for a wide range of applications.
Check Digit Verification of cas no
The CAS Registry Mumber 114059-99-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,0,5 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 114059-99:
(8*1)+(7*1)+(6*4)+(5*0)+(4*5)+(3*9)+(2*9)+(1*9)=113
113 % 10 = 3
So 114059-99-3 is a valid CAS Registry Number.
114059-99-3Relevant articles and documents
Hydroxylation of Alkyl Halides with Water in Ionic Liquid: Significantly Enhanced Nucleophilicity of Water
Kim, Dong Wook,Hong, Dong Jin,Seo, Jai Woong,Kim, Hoon Sik,Kim, Hong Kon,Song, Choong Eui,Chi, Dae Yoon
, p. 3186 - 3189 (2004)
A facile method for the nucleophilic hydroxylation of alkyl halides and mesylates with water has been developed in which the use of ionic liquid as an alternative reaction medium not only enhanced the nucleophilicity of water but also reduced the formation of elimination products predominantly formed under the conventional basic reaction conditions. For example, hydroxylation of model compound 2-(3-bromopropyl)naphthalene (1) to 2-(3-hydroxypropyl)-naphthalene (2) with water in 1-n-butyl-3-methylimidazolium tetrafluoroborate ([bmim] [BF 4]) and 1,4-dioxane proceeded selectively in high yield (94%). The reactivity of other nucleophilic oxygen sources such as alcohol, phenol, and acetic acid in an ionic liquid was also investigated.
Preparation method of pyridine quinazoline intermediate (by machine translation)
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Paragraph 0010-0011; 0015-0016; 0020-0021; 0025-0026; 0030, (2020/11/02)
N - alkylation reaction is firstly carried out on 3 - (hydrazinomethyl) pyridine and 2 - (chloromethyl) aniline followed by benzene ring substitution reaction to obtain 6 - (perfluoropropane -2 - yl) -3 - ((pyridin -3 - methylene) amino) -3 and 4 -dihydroquinazoline -2 (1H)-one. In this route, 2 - methylaniline benzyl chloride reaction is many, the design is carried out in the preceding step, 2 - (chloromethyl) aniline is subjected to high vacuum rectification, 95.0-97 .0% is reached, and impurities in subsequent reactions are reduced. In addition, the expensive raw material 2 - bromoheptafluoropropane is reacted in the following step, the raw material cost is reduced, and the total yield is 72.0-74 .0% (in 2 - bromoheptafluoropropane). (by machine translation)
