114873-52-8Relevant articles and documents
Synthesis of macrocyclic bifunctional chelating agents: 1,4,7-tris(carboxymethyl)-10-(2-aminoethyl)-1,4,7,10-tetraazacyclododecane and 1,4,8-tris(carboxymethyl)-11-(2-aminoethyl)-1,4,8,11-tetraazacyclotetradecane
Mishra,Chatal
, p. 336 - 339 (2001)
The convenient, synthetically useful bifunctional chelating agents, 1,4,7-tris(carboxymethyl)-10-(2-aminoethyl)-1,4,7,10-tetraazacyclododecane and 1,4,8-tris(carboxymethyl)-11-(2-aminoethyl)-1,4,8,11- tetraazacyclotetradecane, were obtained by reaction of ethyl bromoacetate with 1,4,7,10-tetraazacyclododecane and 1,4,8,11-tetraazacyclotetradecane, followed by reaction with N-(2-bromoethyl)phthalimide. This method is proven to be more efficient to prepare bifunctional chelating agents with aliphatic side arms in high yields, above 53%.
Using the Ugi multicomponent condensation reaction to prepare families of chromophore appended azamacrocycles and their complexes
Main, Marcus,Snaith, John S.,Meloni, Marco M.,Jauregui, Maitey,Sykes, Daniel,Faulkner, Stephen,Kenwright, Alan M.
supporting information; experimental part, p. 5212 - 5214 (2009/03/12)
The Ugi reaction offers an effective method for preparing chromophore-appended DOTA-monoamide ligands, which can readily be elaborated to their lanthanide complexes. The Royal Society of Chemistry.
Synthesis of conjugated diacetylene, metal-chelating monomers for polymerizable monolayer assemblies.
Roy,Mallik
, p. 1877 - 1879 (2007/10/03)
[see structure]. Self-assembled monolayers (SAMs) of thiols on gold have been used for numerous applications. For protein targeting applications, one successful strategy is to use a metal-chelating SAM. It has also been demonstrated that polymerized SAMs