114880-33-0Relevant articles and documents
Sandwich immunoassay as a high-throughput screening method for cross-coupling reactions
Vicennati, Paola,Bensel, Nicolas,Wagner, Alain,Creminon, Christophe,Taran, Frederic
, p. 6863 - 6866 (2005)
Catalyst sandwich: An efficient and sensitive high-throughput-screening method that uses sandwich immunoassays was developed and applied to the Sonogashira reaction. This new method is amenable to coupling reactions and allows the screening of more than 1
Intercepting the Banert cascade with nucleophilic fluorine: Direct access to α-fluorinated: N H-1,2,3-triazoles
Alexander,Kevorkian,Topczewski
supporting information, p. 5024 - 5027 (2021/05/28)
The treatment of propargylic azides with silver(i) fluoride in acetonitrile was found to yield α-fluorinated NH-1,2,3-triazoles via the Banert cascade. The reaction was regioselective and the products result from an initial [3,3] rearrangement. The reacti
Pyrazine- and pyridine-substituted prop-2-yn-1-ols, but-3-yn-2-ols, and but-3-yn-2-ones –purification, stability, and handling revised
Schindler, Claudia,Schulzke, Carola
, p. 1008 - 1013 (2016/08/26)
A short series of alkynyl-substituted pyrazine and pyridine derivatives was synthesized by the palladium-catalyzed Sonogashira cross-coupling reactions between aryl halides and alkynes. All the products are either white solids or colorless liquids, which is partly in contrast to previous reports. After purification, a color change or intense darkening was observed, in some cases starting almost immediately. Both, the nature of the heteroaromatic ring and the substituents of the alkyne moiety affect their stability. Herein details of synthesis, characterization, and, most importantly, purification and handling are reported.
