114883-84-0 Usage
General Description
(R)-1-Benzyl-pyrrolidine-2-carboxylic acid amide is a chemical compound also known as R-(-)-1-Benzyl-2-pyrrolidinone, which is a chiral compound used in organic synthesis and pharmaceutical research. It is a key intermediate in the production of a variety of pharmaceuticals and drugs, particularly those with potential antipsychotic and neuroprotective properties. Additionally, this compound has been studied for its potential use as a chiral resolving agent in chromatography. Its ability to specifically interact with certain molecules makes it an important building block in the synthesis of various pharmaceutical compounds and is an important compound for research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 114883-84-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,8,8 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 114883-84:
(8*1)+(7*1)+(6*4)+(5*8)+(4*8)+(3*3)+(2*8)+(1*4)=140
140 % 10 = 0
So 114883-84-0 is a valid CAS Registry Number.
114883-84-0Relevant articles and documents
Amidation of esters assisted by Mg(OCH3)2 or CaCl2
Bundesmann, Mark W.,Coffey, Steven B.,Wright, Stephen W.
experimental part, p. 3879 - 3882 (2010/08/19)
Magnesium methoxide (Mg(OCH3)2) and calcium chloride have been shown to facilitate the direct aminolysis of esters by ammonia to primary amides. Methyl, ethyl, isopropyl, and tert-butyl esters were converted to the corresponding carboxamides in good yields. Reactions have been run on a larger scale and without the safety liability inherent in the use of magnesium nitride (Mg3N2). Ammonium chloride and amine hydrochlorides have been used successfully in the place of ammonia with magnesium methoxide.
