116-52-9Relevant articles and documents
Novel urokinase inhibitors
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, (2008/06/13)
The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases.
Radioimaging probes and the use thereof
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, (2008/06/13)
The present invention provides novel radioimaging probes for use in combination with clinical radioimaging techniques for the visualization of specific tissues or regions of the body. These probes can be packaged into a blood-borne delivery vehicle for targeted delivery to these specific tissues or regions. This invention further provides for the use of synthetic microemulsions or chemically modified human low-density lipoprotein (LDL), such as acetylated LDL (AcLDL), as delivery vehicles to target the radioimaging probes specifically to tissues or regions that contain high concentrations of LDL receptors.
Methods and compositions for gene delivery
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, (2008/06/13)
The present invention provides novel compositions and formulations for delivering anionic compounds, particularly polynucleotides (DNA and RNA), across cellular boundaries (e.g., cellular membranes) either in vivo or in vitro.