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116303-65-2

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116303-65-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 116303-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,0 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 116303-65:
(8*1)+(7*1)+(6*6)+(5*3)+(4*0)+(3*3)+(2*6)+(1*5)=92
92 % 10 = 2
So 116303-65-2 is a valid CAS Registry Number.
InChI:InChI=1/C110H162N26O35S5/c1-9-55(6)88(108(168)134-87(54(4)5)107(167)129-77(110(170)171)40-59-45-115-64-22-14-13-21-62(59)64)135-102(162)76(44-86(148)149)127-93(153)67(29-31-82(140)141)120-99(159)73(41-60-46-114-52-116-60)125-106(166)81(51-175)132-98(158)71(38-57-19-11-10-12-20-57)124-97(157)72(39-58-25-27-61(139)28-26-58)123-96(156)70(37-53(2)3)122-105(165)80(50-174)131-94(154)68(30-32-83(142)143)119-91(151)65(23-15-17-34-111)117-101(161)75(43-85(146)147)128-109(169)89(56(7)138)136-95(155)69(33-36-176-8)121-100(160)74(42-84(144)145)126-92(152)66(24-16-18-35-112)118-104(164)79(49-173)133-103(163)78(47-137)130-90(150)63(113)48-172/h10-14,19-22,25-28,45-46,52-56,63,65-81,87-89,115,137-139,172-175H,9,15-18,23-24,29-44,47-51,111-113H2,1-8H3,(H,114,116)(H,117,161)(H,118,164)(H,119,151)(H,120,159)(H,121,160)(H,122,165)(H,123,156)(H,124,157)(H,125,166)(H,126,152)(H,127,153)(H,128,169)(H,129,167)(H,130,150)(H,131,154)(H,132,158)(H,133,163)(H,134,168)(H,135,162)(H,136,155)(H,140,141)(H,142,143)(H,144,145)(H,146,147)(H,

116303-65-2Upstream product

116303-65-2Downstream Products

116303-65-2Related news

The endothelin peptides ET-1, ET-2, ET-3 and SARAFOTOXIN S6B (cas 116303-65-2) are co-mitogenic with platelet-derived growth factor for vascular smooth muscle cells08/11/2019

We have investigated whether any of the three isoforms of endothelin (ET) ET-1, ET-2 and ET-3 or the structurally similar peptide sarafotoxin S6b is mitogenic on its own for rat vascular smooth muscle cells in culture. DNA synthesis was determined by a peroxidase-linked double antibody technique...detailed

Cardiac and vascular actions of SARAFOTOXIN S6B (cas 116303-65-2) and endothelin-108/08/2019

Snake venom-derived sarafotoxin S6B (SRT) and porcine endothelium-derived endothelin-1 (ET) have striking structural similarities. In conscious, freely-moving rats, ET (0.67 nmol/kg) produced a transient tachycardia and fall in arterial blood pressure which was followed by a long-lasting increas...detailed

Cardiac output effects of endothelin-1, -2 and -3 and SARAFOTOXIN S6B (cas 116303-65-2) in conscious rats08/07/2019

Conscious, Long-Evans rats, chronically-instrumented for the direct measurement of intra-arterial and central venous pressures and ascending aortic blood flow (i.e. cardiac output), were given bolus, intravenous doses (4 and 40 pmol) of endothelin-1, -2, or -3 or sarafotoxin S6b in random order....detailed

Endothelin and SARAFOTOXIN S6B (cas 116303-65-2) have similar vasoconstrictor effects and postsynaptically mediated mechanisms08/03/2019

In the isolated perfused mesenteric vascular bed, porcine endothelin (ET) and sarafotoxin S6b produced direct vasoconstriction and potentiated nerve stimulation-induced vasoconstriction. ET also enhanced the vasoconstrictor response to exogenous norepinephrine (NE). Basal or stimulated endogenou...detailed

Atypical receptors mediate the response to endothelin-1 and SARAFOTOXIN S6B (cas 116303-65-2) in the human umbilical artery08/02/2019

The receptors mediating smooth muscle response to endothelin-1 and sarafotoxin S6b in the human umbilical artery were investigated in vitro. Both agonists induced contractions that were unaffected by the endothelin ETB receptor antagonist BQ 788 (10−9, 10−8, 10−7 M). The non-selective endothelin...detailed

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